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Anti-Thioredoxin Polyclonal Antibody
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Catalog No. TMAB-13509
Anti-Thioredoxin Polyclonal Antibody is a Rabbit antibody targeting Thioredoxin. Anti-Thioredoxin Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,FCM,ELISA.
Anti-Thioredoxin Polyclonal Antibody
Anti-Thioredoxin Polyclonal Antibody
😃Good
Catalog No. TMAB-13509
Anti-Thioredoxin Polyclonal Antibody is a Rabbit antibody targeting Thioredoxin. Anti-Thioredoxin Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,FCM,ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Thioredoxin Polyclonal Antibody is a Rabbit antibody targeting Thioredoxin. Anti-Thioredoxin Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,FCM,ELISA. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; FCM: 1µg/Test; ELISA: 1:1000-5000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. Secreted. Note=Secreted by a leaderless secretory pathway. Predominantly in the cytoplasm in non irradiated cells. Radiation induces translocation of TRX from the cytoplasm to the nucleus. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| Immunogen | KLH conjugated synthetic peptide: human Thioredoxin |
| Antigen Species | Human |
| Gene Name | TXN |
| Gene ID | |
| Protein Name | Thioredoxin |
| Uniprot ID | |
| Function | Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. |
| Molecular Weight | Theoretical: 12 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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