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Anti-LRIT1 Polyclonal Antibody

Catalog No. TMAB-08392 Copy Product Info
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Anti-LRIT1 Polyclonal Antibody is a Rabbit antibody targeting LRIT1. Anti-LRIT1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-LRIT1 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-08392

Anti-LRIT1 Polyclonal Antibody is a Rabbit antibody targeting LRIT1. Anti-LRIT1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-LRIT1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-LRIT1 Polyclonal Antibody is a Rabbit antibody targeting LRIT1. Anti-LRIT1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Cow,Horse)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (LRIT1) Polyclonal Antibody, Unconjugated (TMAB-08392) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum membrane.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 21 (LRRC21), also designated leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 (LRIT1) or PAL, is a 623 amino acid protein that contains 6 LRR repeats. LRRC21 is expressed in retina and may play a role in phototransduction.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human LRIT1
Antigen Species
Human
Gene Name
LRIT1
Gene ID
Protein Name
Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1
Uniprot ID
Function
Possible role in phototransduction.
Chemical Properties
Molecular WeightTheoretical: 66 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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