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Anti-TYK2 Polyclonal Antibody

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Catalog No. TMAB-13908

Anti-TYK2 Polyclonal Antibody is a Rabbit antibody targeting TYK2. Anti-TYK2 Polyclonal Antibody can be used in WB.

Anti-TYK2 Polyclonal Antibody

Anti-TYK2 Polyclonal Antibody

😃Good
Catalog No. TMAB-13908
Anti-TYK2 Polyclonal Antibody is a Rabbit antibody targeting TYK2. Anti-TYK2 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-TYK2 Polyclonal Antibody is a Rabbit antibody targeting TYK2. Anti-TYK2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,GuineaPig)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Tissue SpecificityObserved in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human TYK2
Antigen Species
Human
Gene Name
TYK2
Gene ID
Protein Name
Non-receptor tyrosine-protein kinase TYK2
Uniprot ID
Function
Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain.
Chemical Properties
Molecular WeightTheoretical: 134 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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