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Anti-TYK2 Polyclonal Antibody

Catalog No. TMAB-13908 Copy Product Info
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Anti-TYK2 Polyclonal Antibody is a Rabbit antibody targeting TYK2. Anti-TYK2 Polyclonal Antibody can be used in WB.

Anti-TYK2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-13908

Anti-TYK2 Polyclonal Antibody is a Rabbit antibody targeting TYK2. Anti-TYK2 Polyclonal Antibody can be used in WB.

Anti-TYK2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-TYK2 Polyclonal Antibody is a Rabbit antibody targeting TYK2. Anti-TYK2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,GuineaPig)
Verified Activity
1. Sample: A549 (Human) Cell Lysate at 30 μg
Primary: Anti-TYK2 (TMAB-13908) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 134 kD
Observed band size: 134 kD
2. Sample:
Lane 1: Human HeLa cell lysates
Lane 2: Human MCF-7 cell lysates
Primary: Anti-TYK2 (TMAB-13908) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 134 kDa
Observed band size: 134 kDa
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Tissue SpecificityObserved in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human TYK2
Antigen Species
Human
Gene Name
TYK2
Gene ID
Protein Name
Non-receptor tyrosine-protein kinase TYK2
Uniprot ID
Function
Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain.
Chemical Properties
Molecular WeightTheoretical: 134 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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