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Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2

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Catalog No. TMAB-11071

Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Numb (Ser276). Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2 can be used in WB.

Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2

Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2

😃Good
Catalog No. TMAB-11071
Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Numb (Ser276). Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2 can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Numb (Ser276). Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Peripheral membrane protein.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: human Numb around the phosphorylation site of Ser276
Antigen Species
Human
Gene Name
NUMB
Gene ID
Protein Name
Protein numb homolog
Uniprot ID
Function
Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.
Chemical Properties
Molecular WeightTheoretical: 70 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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