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Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2
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Catalog No. TMAB-11071 Copy Product Info
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Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Numb (Ser276). Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2 can be used in WB.
Anti-Phospho-Numb
(Ser276) Polyclonal Antibody 2
(Ser276) Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Numb (Ser276). Anti-Phospho-Numb (Ser276) Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Peripheral membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human Numb around the phosphorylation site of Ser276 |
| Antigen Species | Human |
| Gene Name | NUMB |
| Gene ID | |
| Protein Name | Protein numb homolog |
| Uniprot ID | |
| Function | Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage. |
| Molecular Weight | Theoretical: 70 kDa. Actual: 75 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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