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Anti-BNC1 Polyclonal Antibody 2
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Catalog No. TMAB-03174
Anti-BNC1 Polyclonal Antibody 2 is a Rabbit antibody targeting BNC1. Anti-BNC1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Anti-BNC1 Polyclonal Antibody 2
Anti-BNC1 Polyclonal Antibody 2
😃Good
Catalog No. TMAB-03174
Anti-BNC1 Polyclonal Antibody 2 is a Rabbit antibody targeting BNC1. Anti-BNC1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,ICC/IF,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-BNC1 Polyclonal Antibody 2 is a Rabbit antibody targeting BNC1. Anti-BNC1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. Relocates to the midpiece of the flagellum during late spermiogenesis in spermatids. |
| Tissue Specificity | Expressed in epidermis, testis and foreskin, and to a lower extent in thymus, spleen, mammary glands, placenta, brain and heart. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The zinc finger protein, basonuclin, is a putative rDNA transcription factor with highly restricted tissue distribution. Basonuclin is abundantly expressed in keratinocytes of the basal layer of the epidermis, the outer sheath of hair follicles and in the germ cells of the testis and ovary. Although basonuclin is associated with chromatin throughout the cell cycle, including mitosis, it disappears when cells become post-mitotic. In the epidermis, basonuclin, which is mainly localized to the cytoplasm, translocates to basal cell nuclei during different stages of keratinocyte growth. Basonuclin may enhance rRNA synthesis by elevating transcription from an rDNA promoter and inhibiting RNA polymerase I transcription through its zinc finger domain. Therefore, basonuclin may be a cell-type-specific transcription factor for rDNA transcription. |
| Immunogen | KLH conjugated synthetic peptide: human BNC1 |
| Antigen Species | Human |
| Gene Name | BNC1 |
| Gene ID | |
| Protein Name | Zinc finger protein basonuclin-1 |
| Uniprot ID | |
| Function | Likely to be a transcription factor specific for squamous epithelium and for the constituent keratinocytes at a stage either prior to or at the very beginning of terminal differentiation. May play a role in the differentiation of spermatozoa and oocytes. |
| Molecular Weight | Theoretical: 111 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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