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Anti-ZEB1/NIL2A Polyclonal Antibody 2
Catalog No. TMAB-14286 Copy Product Info
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Anti-ZEB1/NIL2A Polyclonal Antibody 2 is a Rabbit antibody targeting ZEB1/NIL2A. Anti-ZEB1/NIL2A Polyclonal Antibody 2 can be used in WB.
Anti-ZEB1/NIL2A Polyclonal Antibody 2
Copy Product Info🥰Excellent
Catalog No. TMAB-14286
Anti-ZEB1/NIL2A Polyclonal Antibody 2 is a Rabbit antibody targeting ZEB1/NIL2A. Anti-ZEB1/NIL2A Polyclonal Antibody 2 can be used in WB.
Anti-ZEB1/NIL2A Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Antigen Details
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| Description | Anti-ZEB1/NIL2A Polyclonal Antibody 2 is a Rabbit antibody targeting ZEB1/NIL2A. Anti-ZEB1/NIL2A Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep) |
| Verified Activity | Sample: Lane 1: Thymus (Mouse) Lysate at 40 μg Lane 2: H9C2 (Human) Cell Lysate at 30 μg Primary: Anti-ZEB1/NIL2A (TMAB-14286) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 110 kD Observed band size: 110 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Colocalizes with SMARCA4/BRG1 in E-cadherin-negative cells from established lines, and stroma of normal colon as well as in de-differentiated epithelial cells at the invasion front of colorectal carcinomas (at protein level). Expressed in heart and skeletal muscle, but not in liver, spleen, or pancreas. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2010] |
| Immunogen | KLH conjugated synthetic peptide: human ZEB1/NIL2A |
| Antigen Species | Human |
| Gene Name | ZEB1 |
| Gene ID | |
| Protein Name | Zinc finger E-box-binding homeobox 1 |
| Uniprot ID | |
| Function | Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs. |
| Molecular Weight | Theoretical: 124 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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