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Anti-Methionine Aminopeptidase 2 Polyclonal Antibody

Catalog No. TMAB-08766 Copy Product Info
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Anti-Methionine Aminopeptidase 2 Polyclonal Antibody is a Rabbit antibody targeting Methionine Aminopeptidase 2. Anti-Methionine Aminopeptidase 2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Methionine Aminopeptidase 2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-08766

Anti-Methionine Aminopeptidase 2 Polyclonal Antibody is a Rabbit antibody targeting Methionine Aminopeptidase 2. Anti-Methionine Aminopeptidase 2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Methionine Aminopeptidase 2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Methionine Aminopeptidase 2 Polyclonal Antibody is a Rabbit antibody targeting Methionine Aminopeptidase 2. Anti-Methionine Aminopeptidase 2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Sheep)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Amp2) Polyclonal Antibody, Unconjugated (TMAB-08766) at 1:400 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Methionine Aminopeptidase 2
Antigen Species
Human
Gene Name
METAP2
Gene ID
Protein Name
Methionine aminopeptidase 2
Uniprot ID
Function
Removes the amino-terminal methionine from nascent proteins. The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo.
Chemical Properties
Molecular WeightTheoretical: 53 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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