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Anti-Ube2L6 Polyclonal Antibody

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Catalog No. TMAB-13939

Anti-Ube2L6 Polyclonal Antibody is a Rabbit antibody targeting Ube2L6. Anti-Ube2L6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Ube2L6 Polyclonal Antibody

Anti-Ube2L6 Polyclonal Antibody

😃Good
Catalog No. TMAB-13939
Anti-Ube2L6 Polyclonal Antibody is a Rabbit antibody targeting Ube2L6. Anti-Ube2L6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Ube2L6 Polyclonal Antibody is a Rabbit antibody targeting Ube2L6. Anti-Ube2L6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Tissue SpecificityPresent in natural killer cells.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundUbiquitin is an abundant, highly conserved protein found in all eukaryotic cells, either free or covalently attached to cellular proteins. The primary function of ubiquitin in mammalian systems is to clear abnormal, foreign, and improperly folded proteins by targeting them for proteosome degradation. Ubiquitin conjugating enzyme 8 (UBC8) is an E2 enzyme involved in the ubiquitin pathway for protein degradation. Like other E2 enzymes, UBC8 forms a thioester bond with ubiquitin in an E1-dependent manner. UBC8 binds to the human homolog of Drosophila ariadne (HHARI) and UBC7-associated protein (H7-AP1) as well as double ring-finger protein (Dorfin). UBC8 is enriched in the central nervous system and interacts with Parkin, a RING-finger-containing protein implicated in the pathogenesis of familial Parkinson’s disease. Parkin shares sequence homology with other UBC8 binding proteins such as HHARI and H7-AP1.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Ube2L6
Antigen Species
Human
Gene Name
UBE2L6
Gene ID
9246
Protein Name
Ubiquitin/ISG15-conjugating enzyme E2 L6
Uniprot ID
O14933
Function
Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3.
Chemical Properties
Molecular WeightTheoretical: 18 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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