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Anti-FPRL1 Polyclonal Antibody 3

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Catalog No. TMAB-06153

Anti-FPRL1 Polyclonal Antibody 3 is a Rabbit antibody targeting FPRL1. Anti-FPRL1 Polyclonal Antibody 3 can be used in WB.

Anti-FPRL1 Polyclonal Antibody 3

Anti-FPRL1 Polyclonal Antibody 3

😃Good
Catalog No. TMAB-06153
Anti-FPRL1 Polyclonal Antibody 3 is a Rabbit antibody targeting FPRL1. Anti-FPRL1 Polyclonal Antibody 3 can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-FPRL1 Polyclonal Antibody 3 is a Rabbit antibody targeting FPRL1. Anti-FPRL1 Polyclonal Antibody 3 can be used in WB.
Ig Type
IgG
Reactivity
Mouse
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
Tissue SpecificityExpressed abundantly in the lung and neutrophils. Also found in the spleen and testis.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundFPRL1 is a low affinity receptor to N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). FPRL1 has been reported in phagocytes, monocytes, neutrophils, differentiated myeloid cells from bone marrow, granulocyte HL-60 cells, and synovial fibroblasts. ESTs have been isolated from blood, leukocyte, lung, and placenta libraries.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse FPRL1
Antigen Species
Mouse
Gene Name
FPR2
Gene ID
2358
Protein Name
N-formyl peptide receptor 2
Function
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
Chemical Properties
Molecular WeightTheoretical: 39 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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