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Anti-Phospho-Dab1 (Ser491) Polyclonal Antibody

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Catalog No. TMAB-10572

Anti-Phospho-Dab1 (Ser491) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Dab1 (Ser491). Anti-Phospho-Dab1 (Ser491) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-Phospho-Dab1 (Ser491) Polyclonal Antibody

Anti-Phospho-Dab1 (Ser491) Polyclonal Antibody

Copy Product Info
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Catalog No. TMAB-10572
Anti-Phospho-Dab1 (Ser491) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Dab1 (Ser491). Anti-Phospho-Dab1 (Ser491) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Phospho-Dab1 (Ser491) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Dab1 (Ser491). Anti-Phospho-Dab1 (Ser491) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat,Chicken,Dog,Cow,Horse,Rabbit,Sheep)
Verified Activity
1. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (P-Dab1 (Ser491)) Polyclonal Antibody, Unconjugated (TMAB-10572) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
2. Sample: 293T Cell (Human) Lysate at 40 μg
Primary: Anti-Phospho-Dab1 (Ser491) (TMAB-10572) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 65 kD
Observed band size: 63 kD
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: mouse Dab1 around the phosphorylation site of Ser491
Antigen Species
Mouse
Gene Name
DAB1
Gene ID
Protein Name
Disabled homolog 1
Uniprot ID
Function
Adapter molecule functioning in neural development. May regulate SIAH1 activity.
Chemical Properties
Molecular WeightTheoretical: 65 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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