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Anti-ABCD2 Polyclonal Antibody

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Catalog No. TMAB-02152
Alias hALDR, ATP-binding cassette sub-family D member 2, ALDRP, ALDR, ALDL1, Adrenoleukodystrophy-related protein, Adrenoleukodystrophy-like 1, ABCD2_HUMAN, Abcd2, ABC39

Anti-ABCD2 Polyclonal Antibody is a Rabbit antibody targeting ABCD2. Anti-ABCD2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-ABCD2 Polyclonal Antibody

Anti-ABCD2 Polyclonal Antibody

Copy Product Info
😃Good
Catalog No. TMAB-02152Alias hALDR, ATP-binding cassette sub-family D member 2, ALDRP, ALDR, ALDL1, Adrenoleukodystrophy-related protein, Adrenoleukodystrophy-like 1, ABCD2_HUMAN, Abcd2, ABC39
Anti-ABCD2 Polyclonal Antibody is a Rabbit antibody targeting ABCD2. Anti-ABCD2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-ABCD2 Polyclonal Antibody is a Rabbit antibody targeting ABCD2. Anti-ABCD2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
SynonymshALDR, ATP-binding cassette sub-family D member 2, ALDRP, ALDR, ALDL1, Adrenoleukodystrophy-related protein, Adrenoleukodystrophy-like 1, ABCD2_HUMAN, Abcd2, ABC39
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Sheep)
Verified Activity
1. Sample:
Heart (Mouse) Lysate at 40 μg
Primary: Anti-ABCD2 (TMAB-02152) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 83 kD
Observed band size: 83 kD
2. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (ABCD2) Polyclonal Antibody, Unconjugated (TMAB-02152) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationPeroxisome membrane; Multi-pass membrane protein.
Tissue SpecificityPredominantly expressed in brain and heart.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ABCD2
Antigen Species
Human
Gene Name
Abcd2
Gene ID
Protein Name
ATP-binding cassette sub-family D member 2
Uniprot ID
Function
Probable transporter.
Chemical Properties
Molecular WeightTheoretical: 83 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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