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Anti-ABCD2 Polyclonal Antibody (Synonyms: hALDR, ATP-binding cassette sub-family D member 2, ALDRP, ALDR, AL...)
Catalog No. TMAB-02152 Copy Product Info
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Anti-ABCD2 Polyclonal Antibody is a Rabbit antibody targeting ABCD2. Anti-ABCD2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-ABCD2 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-02152
Synonyms hALDR, ATP-binding cassette sub-family D member 2, ALDRP, ALDR, ALDL1, Adrenoleukodystrophy-related protein, Adrenoleukodystrophy-like 1, ABCD2_HUMAN, Abcd2, ABC39
Anti-ABCD2 Polyclonal Antibody is a Rabbit antibody targeting ABCD2. Anti-ABCD2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-ABCD2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-ABCD2 Polyclonal Antibody is a Rabbit antibody targeting ABCD2. Anti-ABCD2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Synonyms | hALDR, ATP-binding cassette sub-family D member 2, ALDRP, ALDR, ALDL1, Adrenoleukodystrophy-related protein, Adrenoleukodystrophy-like 1, ABCD2_HUMAN, Abcd2, ABC39 |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Sheep) |
| Verified Activity | 1. Sample: Heart (Mouse) Lysate at 40 μg Primary: Anti-ABCD2 (TMAB-02152) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 83 kD Observed band size: 83 kD 2. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (ABCD2) Polyclonal Antibody, Unconjugated (TMAB-02152) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Peroxisome membrane; Multi-pass membrane protein. |
| Tissue Specificity | Predominantly expressed in brain and heart. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human ABCD2 |
| Antigen Species | Human |
| Gene Name | Abcd2 |
| Gene ID | |
| Protein Name | ATP-binding cassette sub-family D member 2 |
| Uniprot ID | |
| Function | Probable transporter. |
| Molecular Weight | Theoretical: 83 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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