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Anti-SOCS6 Polyclonal Antibody
Catalog No. TMAB-13023 Copy Product Info
🥰Excellent
Anti-SOCS6 Polyclonal Antibody is a Rabbit antibody targeting SOCS6. Anti-SOCS6 Polyclonal Antibody can be used in WB.
Anti-SOCS6 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-13023
Anti-SOCS6 Polyclonal Antibody is a Rabbit antibody targeting SOCS6. Anti-SOCS6 Polyclonal Antibody can be used in WB.
Anti-SOCS6 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-SOCS6 Polyclonal Antibody is a Rabbit antibody targeting SOCS6. Anti-SOCS6 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Chicken (predicted:Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | Sample: Heart (Chicken) Lysate at 40 μg Primary: Anti-SOCS6 (TMAB-13023) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 59 kD Observed band size: 60 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated synthetic peptide: human SOCS6 |
| Antigen Species | Human |
| Gene Name | SOCS6 |
| Gene ID | |
| Protein Name | Suppressor of cytokine signaling 6 |
| Uniprot ID | |
| Function | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor. |
| Molecular Weight | Theoretical: 59 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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