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Anti-AIMP2 Polyclonal Antibody

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Catalog No. TMAB-02396

Anti-AIMP2 Polyclonal Antibody is a Rabbit antibody targeting AIMP2. Anti-AIMP2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.

Anti-AIMP2 Polyclonal Antibody

Anti-AIMP2 Polyclonal Antibody

😃Good
Catalog No. TMAB-02396
Anti-AIMP2 Polyclonal Antibody is a Rabbit antibody targeting AIMP2. Anti-AIMP2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-AIMP2 Polyclonal Antibody is a Rabbit antibody targeting AIMP2. Anti-AIMP2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse,Pig,Cow,Rabbit)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm, cytosol (By similarity). Nucleus By similarity). Note=Following DNA damage, dissociates from the minoacyl-tRNA synthase complex and translocates from the cytoplasm o the nucleus (By similarity).
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundP38 is a probable core protein of the multisynthetase complex that serves as a template for the assembly of the supramolecular structure. Mediates ubiquitination of FUBP1 and its degradation by the proteasome. P38 is also a cofactor of multi-ARS complex and also a substrate of parkin in neuronal cell.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human AIMP2
Antigen Species
Human
Gene Name
AIMP2
Gene ID
Protein Name
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
Uniprot ID
Function
Required for assembly and stability of the minoacyl-tRNA synthase complex. Mediates ubiquitination and egradation of FUBP1, a transcriptional activator of MYC, leading o MYC down-regulation which is required for aveolar type II cell ifferentiation. Blocks MDM2-mediated ubiquitination and egradation of p53/TP53. Functions as a proapoptotic factor.
Chemical Properties
Molecular WeightTheoretical: 36 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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