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Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody
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Catalog No. TMAB-11039
Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NFATc2 (Ser326). Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody can be used in FCM.
Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody
Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody
😃Good
Catalog No. TMAB-11039
Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NFATc2 (Ser326). Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NFATc2 (Ser326). Anti-Phospho-NFATc2 (Ser326) Polyclonal Antibody can be used in FCM. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse) |
| Application | |
| Recommended Dose | FCM: 1-2μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. Note=Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription. |
| Tissue Specificity | Expressed in thymus, spleen, heart, testis, brain, placenta, muscle and pancreas. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012] |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human NFATc2 around the phosphorylation site of Ser326 |
| Antigen Species | Human |
| Gene Name | NFATC2 |
| Gene ID | |
| Protein Name | Nuclear factor of activated T-cells, cytoplasmic 2 |
| Uniprot ID | |
| Function | Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway. |
| Molecular Weight | Theoretical: 102 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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