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Anti-IGF2R/M6PR Polyclonal Antibody

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Catalog No. TMAB-07547

Anti-IGF2R/M6PR Polyclonal Antibody is a Rabbit antibody targeting IGF2R/M6PR. Anti-IGF2R/M6PR Polyclonal Antibody can be used in FCM.

Anti-IGF2R/M6PR Polyclonal Antibody

Anti-IGF2R/M6PR Polyclonal Antibody

😃Good
Catalog No. TMAB-07547
Anti-IGF2R/M6PR Polyclonal Antibody is a Rabbit antibody targeting IGF2R/M6PR. Anti-IGF2R/M6PR Polyclonal Antibody can be used in FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity
Description
Anti-IGF2R/M6PR Polyclonal Antibody is a Rabbit antibody targeting IGF2R/M6PR. Anti-IGF2R/M6PR Polyclonal Antibody can be used in FCM.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Cow)
Application
FCM
Recommended Dose
FCM: 1μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationLysosome membrane. Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundTransport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human IGF2R/M6PR
Antigen Species
Human
Gene Name
IGF2R
Gene ID
3482
Protein Name
Cation-independent mannose-6-phosphate receptor
Uniprot ID
P11717
Function
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Chemical Properties
Molecular WeightTheoretical: 300 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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