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Anti-ADAM18 Polyclonal Antibody
Catalog No. TMAB-02285 Copy Product Info
🥰Excellent
Anti-ADAM18 Polyclonal Antibody is a Rabbit antibody targeting ADAM18. Anti-ADAM18 Polyclonal Antibody can be used in WB.
Anti-ADAM18 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-02285
Anti-ADAM18 Polyclonal Antibody is a Rabbit antibody targeting ADAM18. Anti-ADAM18 Polyclonal Antibody can be used in WB.
Anti-ADAM18 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ADAM18 Polyclonal Antibody is a Rabbit antibody targeting ADAM18. Anti-ADAM18 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Dog) |
| Verified Activity | Sample: Heart (Mouse) Lysate at 40 μg Primary: Anti-ADAM18 at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 62 kD Observed band size: 75/50 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed specifically in testis. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | ADAM18 was first described as tMDC III (testis-specific Metalloproteinase-like disintergin-like cysteine-rich protein-III). ADAM18 is a member of the ADAMs family (A Disintegrin And Metalloproteinase), but does not contain the canonical HExxHxxxxH zinc-binding metalloproteinase catalytic site. The domain structure of the fill-length ADAM18 includes a signal sequence, propeptide domain, metalloproteinase-like domain, disintegrin-like domain, cys-rich domain, EGF-like domain, a short spacer region, then the transmembrane domain and a cytoplasmic domain. Like many of the reproductive-specific ADAMS, ADAM18 plays a nonenzymatic role, or (as is the case for ADAMs 1 & 2 (fertilin alpha and beta)), the protein acts in concert with a proteolytically active ADAM to process proteins. Little is known about interactions between ADAM18 and other ADAMs. To date, 4 different sequences for human ADAM18 are published; 739, 715, 182 and 153 amino acids in length. |
| Immunogen | KLH conjugated synthetic peptide: human ADAM18 |
| Antigen Species | Human |
| Gene Name | ADAM18 |
| Gene ID | |
| Protein Name | Disintegrin and metalloproteinase domain-containing protein 18 |
| Function | Sperm surface membrane protein that may be involved in spermatogenesis and fertilization. This is a non catalytic metalloprotease-like protein. |
| Molecular Weight | Theoretical: 62 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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