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Anti-Thrombin heavy chain Polyclonal Antibody

Catalog No. TMAB-13519 Copy Product Info
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Anti-Thrombin heavy chain Polyclonal Antibody is a Rabbit antibody targeting Thrombin heavy chain. Anti-Thrombin heavy chain Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Thrombin heavy chain Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-13519

Anti-Thrombin heavy chain Polyclonal Antibody is a Rabbit antibody targeting Thrombin heavy chain. Anti-Thrombin heavy chain Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Thrombin heavy chain Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Thrombin heavy chain Polyclonal Antibody is a Rabbit antibody targeting Thrombin heavy chain. Anti-Thrombin heavy chain Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Chicken,Pig,Cow,Horse,Rabbit,Fish)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (mouse liver tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Thrombin heavy chain) Polyclonal Antibody, Unconjugated (TMAB-13519) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted, extracellular space.
Tissue SpecificityExpressed by the liver and secreted in plasma.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundDes-gamma carboxyprothrombin (DCP), also known as protein induced by vitamin K absence/antagonist-II (PIVKA-II), is an abnormal form of the coagulation protein, prothrombin. Normally, the prothrombin precursor undergoes post-translational carboxylation (addition of a carboxylic acid group) by gamma-glutamyl carboxylase in the liver prior to secretion into plasma. DCP/PIVKA-II may be detected in people with deficiency of vitamin K (due to poor nutrition or malabsorption) and in those taking warfarin or other medication that inhibits the action of vitamin K.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Thrombin heavy chain
Antigen Species
Human
Gene Name
F2
Gene ID
Protein Name
Prothrombin
Uniprot ID
Function
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
Chemical Properties
Molecular WeightTheoretical: 28/68 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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