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Anti-Thrombin heavy chain Polyclonal Antibody

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Catalog No. TMAB-13519

Anti-Thrombin heavy chain Polyclonal Antibody is a Rabbit antibody targeting Thrombin heavy chain. Anti-Thrombin heavy chain Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Thrombin heavy chain Polyclonal Antibody

Anti-Thrombin heavy chain Polyclonal Antibody

😃Good
Catalog No. TMAB-13519
Anti-Thrombin heavy chain Polyclonal Antibody is a Rabbit antibody targeting Thrombin heavy chain. Anti-Thrombin heavy chain Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Thrombin heavy chain Polyclonal Antibody is a Rabbit antibody targeting Thrombin heavy chain. Anti-Thrombin heavy chain Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Chicken,Pig,Cow,Horse,Rabbit,Fish)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted, extracellular space.
Tissue SpecificityExpressed by the liver and secreted in plasma.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundDes-gamma carboxyprothrombin (DCP), also known as protein induced by vitamin K absence/antagonist-II (PIVKA-II), is an abnormal form of the coagulation protein, prothrombin. Normally, the prothrombin precursor undergoes post-translational carboxylation (addition of a carboxylic acid group) by gamma-glutamyl carboxylase in the liver prior to secretion into plasma. DCP/PIVKA-II may be detected in people with deficiency of vitamin K (due to poor nutrition or malabsorption) and in those taking warfarin or other medication that inhibits the action of vitamin K.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Thrombin heavy chain
Antigen Species
Human
Gene Name
F2
Gene ID
2147
Protein Name
Prothrombin
Uniprot ID
P00734
Function
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
Chemical Properties
Molecular WeightTheoretical: 28/68 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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