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Anti-Phospho-SNAIL+SLUG (Ser246) Polyclonal Antibody

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Catalog No. TMAB-11309

Anti-Phospho-SNAIL+SLUG (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SNAIL+SLUG (Ser246). Anti-Phospho-SNAIL+SLUG (Ser246) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Phospho-SNAIL+SLUG (Ser246) Polyclonal Antibody

Anti-Phospho-SNAIL+SLUG (Ser246) Polyclonal Antibody

😃Good
Catalog No. TMAB-11309
Anti-Phospho-SNAIL+SLUG (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SNAIL+SLUG (Ser246). Anti-Phospho-SNAIL+SLUG (Ser246) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Phospho-SNAIL+SLUG (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SNAIL+SLUG (Ser246). Anti-Phospho-SNAIL+SLUG (Ser246) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse,Pig,Cow,Horse,Rabbit,Sheep)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:400-800; IHC-Fr: 1:400-800; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Cytoplasm. Note=Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs.
Tissue SpecificityExpressed in a variety of tissues with the highest expression in kidney. Expressed in mesenchymal and epithelial cell lines.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthesised phosphopeptide: human SNAIL around the phosphorylation site of Ser246
Antigen Species
Human
Gene Name
SNAI1
Gene ID
6615
Protein Name
Zinc finger protein SNAI1
Uniprot ID
O95863
Function
Involved in the epithelial to mesenchymal transition (EMT) and formation and maintenance of embryonic mesoderm. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription.
Chemical Properties
Molecular WeightTheoretical: 32 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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