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Anti-Phospho-cdc25A (Ser124) Polyclonal Antibody 2

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Catalog No. TMAB-10452

Anti-Phospho-cdc25A (Ser124) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-cdc25A (Ser124). Anti-Phospho-cdc25A (Ser124) Polyclonal Antibody 2 can be used in FCM.

Anti-Phospho-cdc25A (Ser124) Polyclonal Antibody 2

Anti-Phospho-cdc25A (Ser124) Polyclonal Antibody 2

😃Good
Catalog No. TMAB-10452
Anti-Phospho-cdc25A (Ser124) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-cdc25A (Ser124). Anti-Phospho-cdc25A (Ser124) Polyclonal Antibody 2 can be used in FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Phospho-cdc25A (Ser124) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-cdc25A (Ser124). Anti-Phospho-cdc25A (Ser124) Polyclonal Antibody 2 can be used in FCM.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep)
Application
FCM
Recommended Dose
FCM: 1μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundCDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: human cdc25A around the phosphorylation site of Ser124
Antigen Species
Human
Gene Name
CDC25A
Gene ID
993
Protein Name
M-phase inducer phosphatase 1
Uniprot ID
P30304
Function
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.
Chemical Properties
Molecular WeightTheoretical: 59 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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