Anti-Cyclin H Polyclonal Antibody is a Rabbit antibody targeting Cyclin H. Anti-Cyclin H Polyclonal Antibody can be used in WB.

IgG

Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)

Sample: K562 Cell lysate at 30 μg;
Primary: Anti-Cyclin H (TMAB-04842) at 1:300 dilution;
Secondary: HRP conjugated Goat-Anti-rabbit IgG at 1: 5000 dilution;
Predicted band size:38 kD
Observed band size:38 kD

WB: 1:500-2000

Polyclonal

KLH conjugated synthetic peptide: human Cyclin H

Human

CCNH

Cyclin-H

Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.