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Anti-SHFM3 Polyclonal Antibody
😃Good
Catalog No. TMAB-12767
Anti-SHFM3 Polyclonal Antibody is a Rabbit antibody targeting SHFM3. Anti-SHFM3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-SHFM3 Polyclonal Antibody
Anti-SHFM3 Polyclonal Antibody
😃Good
Catalog No. TMAB-12767
Anti-SHFM3 Polyclonal Antibody is a Rabbit antibody targeting SHFM3. Anti-SHFM3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-SHFM3 Polyclonal Antibody is a Rabbit antibody targeting SHFM3. Anti-SHFM3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Expressed in brain, kidney, lung and liver. |
| Tissue Specificity | Expressed in brain, kidney, lung and liver. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling. Involvement in disease:Defects in FBXW4 are a cause of split-hand/foot malformation type 3 (SHFM3) . SHFM3 is an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits. |
| Immunogen | KLH conjugated synthetic peptide: human SHFM3 |
| Antigen Species | Human |
| Gene Name | FBXW4 |
| Gene ID | |
| Protein Name | F-box/WD repeat-containing protein 4 |
| Uniprot ID | |
| Function | Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling. |
| Molecular Weight | Theoretical: 46 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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