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Anti-HSD11B1 Polyclonal Antibody
😃Good
Catalog No. TMAB-07310
Anti-HSD11B1 Polyclonal Antibody is a Rabbit antibody targeting HSD11B1. Anti-HSD11B1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-HSD11B1 Polyclonal Antibody
Anti-HSD11B1 Polyclonal Antibody
😃Good
Catalog No. TMAB-07310
Anti-HSD11B1 Polyclonal Antibody is a Rabbit antibody targeting HSD11B1. Anti-HSD11B1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-HSD11B1 Polyclonal Antibody is a Rabbit antibody targeting HSD11B1. Anti-HSD11B1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Horse (predicted:Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,Sheep) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Widely expressed. Highest expression in liver. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | HSD11B1 is a microsomal enzyme that catalyses the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyse the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene. |
| Immunogen | KLH conjugated synthetic peptide: human HSD11B1 |
| Antigen Species | Human |
| Gene Name | HSD11B1 |
| Gene ID | |
| Protein Name | Corticosteroid 11-beta-dehydrogenase isozyme 1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 32 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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