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Anti-Mannan Binding Lectin Polyclonal Antibody

Catalog No. TMAB-08547 Copy Product Info
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Anti-Mannan Binding Lectin Polyclonal Antibody is a Rabbit antibody targeting Mannan Binding Lectin. Anti-Mannan Binding Lectin Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Mannan Binding Lectin Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-08547

Anti-Mannan Binding Lectin Polyclonal Antibody is a Rabbit antibody targeting Mannan Binding Lectin. Anti-Mannan Binding Lectin Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Mannan Binding Lectin Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Mannan Binding Lectin Polyclonal Antibody is a Rabbit antibody targeting Mannan Binding Lectin. Anti-Mannan Binding Lectin Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Horse)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (human liver tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (MBL2) Polyclonal Antibody, Unconjugated (TMAB-08547) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
Tissue SpecificityPlasma protein produced mainly in the liver.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Mannan Binding Lectin
Antigen Species
Human
Gene Name
MBL2
Gene ID
Protein Name
Mannose-binding protein C
Uniprot ID
Function
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
Chemical Properties
Molecular WeightTheoretical: 27 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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