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Anti-LPHN1 Polyclonal Antibody
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Catalog No. TMAB-08371
Anti-LPHN1 Polyclonal Antibody is a Rabbit antibody targeting LPHN1. Anti-LPHN1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-LPHN1 Polyclonal Antibody
Anti-LPHN1 Polyclonal Antibody
😃Good
Catalog No. TMAB-08371
Anti-LPHN1 Polyclonal Antibody is a Rabbit antibody targeting LPHN1. Anti-LPHN1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-LPHN1 Polyclonal Antibody is a Rabbit antibody targeting LPHN1. Anti-LPHN1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. Cell projection; axon. Cell projection; growth cone. Cell junction; synapse. Cell junction; synapse; presynaptic cell membrane. Cell junction; synapse; synaptosome. Colocalizes with TENM2 on the cell surface, across intercellular junctions and on nerve terminals near synaptic clefts. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008] |
| Immunogen | KLH conjugated synthetic peptide: human LPHN1 |
| Antigen Species | Human |
| Gene Name | ADGRL1 |
| Gene ID | |
| Protein Name | Adhesion G protein-coupled receptor L1 |
| Uniprot ID | |
| Function | Calcium-independent receptor of high affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor propably implicated in the regulation of exocytosis. |
| Molecular Weight | Theoretical: 160 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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