Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-epithelial Sodium Channel gamma Polyclonal Antibody

😃Good
Catalog No. TMAB-05631

Anti-epithelial Sodium Channel gamma Polyclonal Antibody is a Rabbit antibody targeting epithelial Sodium Channel gamma. Anti-epithelial Sodium Channel gamma Polyclonal Antibody can be used in WB.

Anti-epithelial Sodium Channel gamma Polyclonal Antibody

Anti-epithelial Sodium Channel gamma Polyclonal Antibody

😃Good
Catalog No. TMAB-05631
Anti-epithelial Sodium Channel gamma Polyclonal Antibody is a Rabbit antibody targeting epithelial Sodium Channel gamma. Anti-epithelial Sodium Channel gamma Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Product Introduction

Bioactivity
Description
Anti-epithelial Sodium Channel gamma Polyclonal Antibody is a Rabbit antibody targeting epithelial Sodium Channel gamma. Anti-epithelial Sodium Channel gamma Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Rabbit)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationApical cell membrane; Multi-pass membrane protein. Note=Apical membrane of epithelial cells.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundEpithelial sodium channels are amiloride-sensitive members of the Degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels. Members of this superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region. There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein. ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance. ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure. ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel. Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension (Liddel’s syndrome) and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism (PHA-1).
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human epithelial Sodium Channel gamma
Antigen Species
Human
Gene Name
SCNN1G
Gene ID
Protein Name
Epithelial sodium channel subunit gamma
Uniprot ID
Function
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Chemical Properties
Molecular WeightTheoretical: 71 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-epithelial Sodium Channel gamma Polyclonal Antibody | purchase Anti-epithelial Sodium Channel gamma Polyclonal Antibody | Anti-epithelial Sodium Channel gamma Polyclonal Antibody cost | order Anti-epithelial Sodium Channel gamma Polyclonal Antibody | Anti-epithelial Sodium Channel gamma Polyclonal Antibody molecular weight