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Anti-KIF3A Polyclonal Antibody
Catalog No. TMAB-08046 Copy Product Info
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Anti-KIF3A Polyclonal Antibody is a Rabbit antibody targeting KIF3A. Anti-KIF3A Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-KIF3A Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-08046
Anti-KIF3A Polyclonal Antibody is a Rabbit antibody targeting KIF3A. Anti-KIF3A Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-KIF3A Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-KIF3A Polyclonal Antibody is a Rabbit antibody targeting KIF3A. Anti-KIF3A Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (mouse cerebellum tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (KIF3A) Polyclonal Antibody, Unconjugated (TMAB-08046) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, cytoskeleton (Probable). Cell projection, cilium (By similarity). |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The kinesins constitute a large family of microtubule-dependent motor proteins which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C. KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis. KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined. Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate. |
| Immunogen | KLH conjugated synthetic peptide: human KIF3A |
| Antigen Species | Human |
| Gene Name | KIF3A |
| Gene ID | |
| Protein Name | Kinesin-like protein KIF3A |
| Uniprot ID | |
| Function | Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. |
| Molecular Weight | Theoretical: 80 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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