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Anti-CCDC139 Polyclonal Antibody

Catalog No. TMAB-03738 Copy Product Info
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Anti-CCDC139 Polyclonal Antibody is a Rabbit antibody targeting CCDC139. Anti-CCDC139 Polyclonal Antibody can be used in WB.

Anti-CCDC139 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-03738

Anti-CCDC139 Polyclonal Antibody is a Rabbit antibody targeting CCDC139. Anti-CCDC139 Polyclonal Antibody can be used in WB.

Anti-CCDC139 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CCDC139 Polyclonal Antibody is a Rabbit antibody targeting CCDC139. Anti-CCDC139 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human
Verified Activity
25 μg total protein per lane of various lysates (see on figure) probed with CCDC139 polyclonal antibody, unconjugated (TMAB-03738) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundPseudouridination is the isomerization of uridine to pseudouridine. It is the most common posttranscriptional nucleotide modification found in RNA. It is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones which facilitate the correct folding and assembly of tRNAs.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PUS10/CCDC139
Antigen Species
Human
Gene Name
PUS10
Gene ID
Protein Name
tRNA pseudouridine synthase Pus10
Uniprot ID
Function
Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death.
Chemical Properties
Molecular WeightTheoretical: 60 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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