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Anti-EDARADD Polyclonal Antibody
😃Good
Catalog No. TMAB-05435
Anti-EDARADD Polyclonal Antibody is a Rabbit antibody targeting EDARADD. Anti-EDARADD Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-EDARADD Polyclonal Antibody
Anti-EDARADD Polyclonal Antibody
😃Good
Catalog No. TMAB-05435
Anti-EDARADD Polyclonal Antibody is a Rabbit antibody targeting EDARADD. Anti-EDARADD Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
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Antigen Details
Chemical Properties
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| Description | Anti-EDARADD Polyclonal Antibody is a Rabbit antibody targeting EDARADD. Anti-EDARADD Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,Sheep) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | Detected in adult pancreas, placenta and fetal skin, and at lower levels in lung, thymus, prostate and testis. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human EDARADD |
| Antigen Species | Human |
| Gene Name | EDARADD |
| Gene ID | |
| Protein Name | Ectodysplasin-A receptor-associated adapter protein |
| Uniprot ID | |
| Function | Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF-kappa-B. |
| Molecular Weight | Theoretical: 25 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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