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Anti-Rab3A+Rab3B+Rab3C+Rab3D Polyclonal Antibody

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Catalog No. TMAB-11994

Anti-Rab3A+Rab3B+Rab3C+Rab3D Polyclonal Antibody is a Rabbit antibody targeting Rab3A+Rab3B+Rab3C+Rab3D. Anti-Rab3A+Rab3B+Rab3C+Rab3D Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-Rab3A+Rab3B+Rab3C+Rab3D Polyclonal Antibody

Anti-Rab3A+Rab3B+Rab3C+Rab3D Polyclonal Antibody

Copy Product Info
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Catalog No. TMAB-11994
Anti-Rab3A+Rab3B+Rab3C+Rab3D Polyclonal Antibody is a Rabbit antibody targeting Rab3A+Rab3B+Rab3C+Rab3D. Anti-Rab3A+Rab3B+Rab3C+Rab3D Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Rab3A+Rab3B+Rab3C+Rab3D Polyclonal Antibody is a Rabbit antibody targeting Rab3A+Rab3B+Rab3C+Rab3D. Anti-Rab3A+Rab3B+Rab3C+Rab3D Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human)
Verified Activity
1. Sample: Eye (Mouse) Lysate at 40 μg
Primary: Anti-Rab3A+Rab3B+Rab3C+Rab3D (TMAB-11994) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 24-27 kD
Observed band size: 24 kD
2. Paraformaldehyde-fixed, paraffin embedded (rat heart); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Rab3A+Rab3B+Rab3C+Rab3D) Polyclonal Antibody, Unconjugated (TMAB-11994) at 1:400 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining.
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Lipid-anchor; Cytoplasmic side (Potential).
Tissue SpecificitySpecifically expressed in brain.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundRAB3A (RAB3A, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB3A include Growth Hormone Deficiency, Isolated, Type Ii. Among its related pathways are Innate Immune System and Neurotransmitter Release Cycle. GO annotations related to this gene include GTP binding and protein C-terminus binding. An important paralog of this gene is RAB3C.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Rab3A+Rab3B+Rab3C+Rab3D
Antigen Species
Human
Gene Name
RAB3A
Gene ID
Protein Name
Ras-related protein Rab-3A
Uniprot ID
Function
Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
Chemical Properties
Molecular WeightTheoretical: 24-27 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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