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Anti-FHOD3 Polyclonal Antibody

😃Good
Catalog No. TMAB-06016

Anti-FHOD3 Polyclonal Antibody is a Rabbit antibody targeting FHOD3. Anti-FHOD3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-FHOD3 Polyclonal Antibody

Anti-FHOD3 Polyclonal Antibody

😃Good
Catalog No. TMAB-06016
Anti-FHOD3 Polyclonal Antibody is a Rabbit antibody targeting FHOD3. Anti-FHOD3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-FHOD3 Polyclonal Antibody is a Rabbit antibody targeting FHOD3. Anti-FHOD3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Chicken,Pig,Cow,Horse,Rabbit,Sheep)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm; cytoskeleton. Main part of the protein localizes to actin fibers and the remaining part displays filamentous staining.
Tissue SpecificityExpressed in the heart, kidney and brain.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundFHOD3 (formin homology 2 domain containing 3), also known as FHOS2 or KIAA1695, is a 1,422 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one DAD domain, one FH1 domain, one FH2 domain and one GBD/FH3 domain. Expressed in brain, heart and kidney, FHOD3 interacts with intermediate filaments and functions as an Actin-organizing protein that is thought to promote the formation of stress fibers in conjunction with cellular elongation. Multiple isoforms of FHOD3 exist due to alternative splicing events. The gene encoding FHOD3 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Supervillin
Antigen Species
Human
Gene Name
FHOD3
Gene ID
Protein Name
FH1/FH2 domain-containing protein 3
Uniprot ID
Function
Actin-organizing protein that may cause stress fiber formation together with cell elongation.
Chemical Properties
Molecular WeightTheoretical: 159 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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