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Anti-FHOD3 Polyclonal Antibody
Catalog No. TMAB-06016 Copy Product Info
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Anti-FHOD3 Polyclonal Antibody is a Rabbit antibody targeting FHOD3. Anti-FHOD3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-FHOD3 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-06016
Anti-FHOD3 Polyclonal Antibody is a Rabbit antibody targeting FHOD3. Anti-FHOD3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-FHOD3 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-FHOD3 Polyclonal Antibody is a Rabbit antibody targeting FHOD3. Anti-FHOD3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Chicken,Pig,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | 1. Tissue/cell: Rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-FHOD3 Polyclonal Antibody, Unconjugated (TMAB-06016) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining 2. Tissue/cell: Rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-FHOD3 Polyclonal Antibody, Unconjugated (TMAB-06016) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining 3. Tissue/cell: Rat kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-FHOD3 Polyclonal Antibody, Unconjugated (TMAB-06016) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm; cytoskeleton. Main part of the protein localizes to actin fibers and the remaining part displays filamentous staining. |
| Tissue Specificity | Expressed in the heart, kidney and brain. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | FHOD3 (formin homology 2 domain containing 3), also known as FHOS2 or KIAA1695, is a 1,422 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one DAD domain, one FH1 domain, one FH2 domain and one GBD/FH3 domain. Expressed in brain, heart and kidney, FHOD3 interacts with intermediate filaments and functions as an Actin-organizing protein that is thought to promote the formation of stress fibers in conjunction with cellular elongation. Multiple isoforms of FHOD3 exist due to alternative splicing events. The gene encoding FHOD3 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. |
| Immunogen | KLH conjugated synthetic peptide: human Supervillin |
| Antigen Species | Human |
| Gene Name | FHOD3 |
| Gene ID | |
| Protein Name | FH1/FH2 domain-containing protein 3 |
| Uniprot ID | |
| Function | Actin-organizing protein that may cause stress fiber formation together with cell elongation. |
| Molecular Weight | Theoretical: 159 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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