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Anti-IL12RB2 Polyclonal Antibody
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Catalog No. TMAB-07601
Anti-IL12RB2 Polyclonal Antibody is a Rabbit antibody targeting IL12RB2. Anti-IL12RB2 Polyclonal Antibody can be used in WB,ELISA.
Anti-IL12RB2 Polyclonal Antibody
Anti-IL12RB2 Polyclonal Antibody
😃Good
Catalog No. TMAB-07601
Anti-IL12RB2 Polyclonal Antibody is a Rabbit antibody targeting IL12RB2. Anti-IL12RB2 Polyclonal Antibody can be used in WB,ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-IL12RB2 Polyclonal Antibody is a Rabbit antibody targeting IL12RB2. Anti-IL12RB2 Polyclonal Antibody can be used in WB,ELISA. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse) |
| Application | |
| Recommended Dose | WB: 1:500-2000; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single pass type I membrane protein. |
| Tissue Specificity | Isoform 2 is expressed at similar levels in both naive and activated T-cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. [provided by RefSeq]. |
| Immunogen | KLH conjugated synthetic peptide: human IL-12RB2 |
| Antigen Species | Human |
| Gene Name | IL12RB2 |
| Gene ID | |
| Protein Name | Interleukin-12 receptor subunit beta-2 |
| Uniprot ID | |
| Function | Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production. |
| Molecular Weight | Theoretical: 95 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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