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Anti-FARP1 Polyclonal Antibody is a Rabbit antibody targeting FARP1. Anti-FARP1 Polyclonal Antibody can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-FARP1 Polyclonal Antibody is a Rabbit antibody targeting FARP1. Anti-FARP1 Polyclonal Antibody can be used in FCM. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasmic. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | FARP1 (FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1), also known as PLEKHC2 or CDEP, is a 1,045 amino acid protein that contains one FERM domain, one DH domain and two PH domains. Existing as multiple alternatively spliced isoforms that are expressed in fetal heart, brain and spleen, as well as in adult lung, kidney and testis, FARP1 is thought to function as a Rho-guanine nucleotide exchange factor that may play a role in linking the cell membrane to the cytoskeleton. The gene encoding FARP1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. |
| Immunogen | KLH conjugated synthetic peptide: human FARP1 |
| Antigen Species | Human |
| Gene Name | FARP1 |
| Gene ID | |
| Protein Name | FERM, ARHGEF and pleckstrin domain-containing protein 1 |
| Uniprot ID | |
| Function | The FARP1 protein contains a predicted ezrin-like domain, a Dbl homology domain, and a pleckstrin homology domain, and is believed to be a member of the band 4.1 superfamily, whose members link the cytoskeleton to the cell membrane. Two alternatively spliced transcript variants encoding distinct isoforms have been found for the FARP1 gene, which shows increased expression in differentiated chondrocytes versus dedifferentiated chondrocytes. |
| Molecular Weight | Theoretical: 119 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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