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Anti-Connexin 31.1 Polyclonal Antibody
Catalog No. TMAB-04560 Copy Product Info
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Anti-Connexin 31.1 Polyclonal Antibody is a Rabbit antibody targeting Connexin 31.1. Anti-Connexin 31.1 Polyclonal Antibody can be used in WB.
Anti-Connexin 31.1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-04560
Anti-Connexin 31.1 Polyclonal Antibody is a Rabbit antibody targeting Connexin 31.1. Anti-Connexin 31.1 Polyclonal Antibody can be used in WB.
Anti-Connexin 31.1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Connexin 31.1 Polyclonal Antibody is a Rabbit antibody targeting Connexin 31.1. Anti-Connexin 31.1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | Sample: Raw264.7 (Mouse) Cell Lysate at 30 μg Primary: Anti-Connexin 31.1 (TMAB-04560) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kD Observed band size: 31 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. Cell junction > gap junction. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The connexin family of proteins form hexameric complexes, called connexons, that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane ?helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino acid substitutions in the most highly conserved domains; the transmembrane and extracellular regions. Connexin 31.1, Cx31.1 or Gap junction beta-5 protein, is a 271 amino acid protein that is predominantly expressed in skin with lower expression in testis. Expression of connexin 31.1 is required for normal placental development in mice. Down-regulation of the connexin 31.1 gene correlates with head and neck squamous cell carcinomas (HNSCC) and therefore it may be a potential therapeutic target. |
| Immunogen | KLH conjugated synthetic peptide: human Connexin 31.1 |
| Antigen Species | Human |
| Gene Name | GJB5 |
| Gene ID | |
| Protein Name | Gap junction beta-5 protein |
| Uniprot ID | |
| Function | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. |
| Molecular Weight | Theoretical: 31 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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