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Anti-Calcipressin 1/DSCR 1 Polyclonal Antibody

Catalog No. TMAB-03564 Copy Product Info
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Anti-Calcipressin 1/DSCR 1 Polyclonal Antibody is a Rabbit antibody targeting Calcipressin 1/DSCR 1. Anti-Calcipressin 1/DSCR 1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Calcipressin 1/DSCR 1 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-03564

Anti-Calcipressin 1/DSCR 1 Polyclonal Antibody is a Rabbit antibody targeting Calcipressin 1/DSCR 1. Anti-Calcipressin 1/DSCR 1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Calcipressin 1/DSCR 1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Calcipressin 1/DSCR 1 Polyclonal Antibody is a Rabbit antibody targeting Calcipressin 1/DSCR 1. Anti-Calcipressin 1/DSCR 1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Pig,Horse,Rabbit,Sheep)
Verified Activity
Tissue/cell: human kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min;
Incubation: Anti-DSCR1 Polyclonal Antibody, Unconjugated (TMAB-03564) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Tissue SpecificityHighly expressed heart, brain and skeletal muscle. Also expressed in all other tissues.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Calcipressin 1
Antigen Species
Human
Gene Name
RCAN1
Gene ID
1827
Protein Name
Calcipressin-1
Uniprot ID
P53805
Function
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
Chemical Properties
Molecular WeightTheoretical: 28 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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