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Anti-AFAP1L2 Polyclonal Antibody
😃Good
Catalog No. TMAB-02373
Anti-AFAP1L2 Polyclonal Antibody is a Rabbit antibody targeting AFAP1L2. Anti-AFAP1L2 Polyclonal Antibody can be used in WB,FCM.
Anti-AFAP1L2 Polyclonal Antibody
Anti-AFAP1L2 Polyclonal Antibody
😃Good
Catalog No. TMAB-02373
Anti-AFAP1L2 Polyclonal Antibody is a Rabbit antibody targeting AFAP1L2. Anti-AFAP1L2 Polyclonal Antibody can be used in WB,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-AFAP1L2 Polyclonal Antibody is a Rabbit antibody targeting AFAP1L2. Anti-AFAP1L2 Polyclonal Antibody can be used in WB,FCM. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 2μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Actin filament associated protein (AFAP-110) interacts directly with actin filaments through its C-terminal actin-binding domain. AFAP-110 contains additional protein-binding domains as well, and serves as an adaptor protein. By linking signaling molecules to actin filaments, AFAP-110 provides a platform for the preparation of larger signaling complexes, activates Src kinases in response to cellular signals and also directly affects Actin organization as an Actin filament cross-linking protein. AFAP-1L2 (Actin filament-associated protein 1-like 2), also known as XB130, is a 818 amino acid cytoplasmic protein that contains two Pleckstrin homology (PH) domains, which are normally found in proteins involved in intracellular signaling. Like its relative AFAP110, AFAP-1L2 interacts with Src kinase and may play a role in Src-regulated transcription activation. AFAP-1L2 is expressed in thyroid and spleen and can also be detected at lower levels in lung, brain, pancreas and kidney. There are four isoforms of AFAP-1L2 that are produced as a result of alternative splicing events. |
| Immunogen | KLH conjugated synthetic peptide: human AFAP1L2 |
| Antigen Species | Human |
| Gene Name | AFAP1L2 |
| Gene ID | |
| Protein Name | Actin filament-associated protein 1-like 2 |
| Uniprot ID | |
| Function | May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation. |
| Molecular Weight | Theoretical: 90 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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