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Anti-TIM4 Polyclonal Antibody 3

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Catalog No. TMAB-13544

Anti-TIM4 Polyclonal Antibody 3 is a Rabbit antibody targeting TIM4. Anti-TIM4 Polyclonal Antibody 3 can be used in WB.

Anti-TIM4 Polyclonal Antibody 3

Anti-TIM4 Polyclonal Antibody 3

😃Good
Catalog No. TMAB-13544
Anti-TIM4 Polyclonal Antibody 3 is a Rabbit antibody targeting TIM4. Anti-TIM4 Polyclonal Antibody 3 can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-TIM4 Polyclonal Antibody 3 is a Rabbit antibody targeting TIM4. Anti-TIM4 Polyclonal Antibody 3 can be used in WB.
Ig Type
IgG
Reactivity
Mouse
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein (Potential).
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. Studies have shown that TIM 4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM 1, and that this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM 4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM 4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM 1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse TIM4
Antigen Species
Mouse
Gene Name
TIMD4
Gene ID
Protein Name
T-cell immunoglobulin and mucin domain-containing protein 4
Uniprot ID
Function
Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Involved in regulating T-cell proliferation and lymphotoxin signaling. Ligand for HAVCR1/TIMD1 (By similarity).
Chemical Properties
Molecular WeightTheoretical: 42 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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