Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-ERBB3 Polyclonal Antibody

😃Good
Catalog No. TMAB-05650

Anti-ERBB3 Polyclonal Antibody is a Rabbit antibody targeting ERBB3. Anti-ERBB3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-ERBB3 Polyclonal Antibody

Anti-ERBB3 Polyclonal Antibody

😃Good
Catalog No. TMAB-05650
Anti-ERBB3 Polyclonal Antibody is a Rabbit antibody targeting ERBB3. Anti-ERBB3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Product Introduction

Bioactivity
Description
Anti-ERBB3 Polyclonal Antibody is a Rabbit antibody targeting ERBB3. Anti-ERBB3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse,Chicken,Dog,Cow,Horse,Rabbit)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationIsoform 1: Cell membrane; Single-pass type I. membrane protein. Isoform 2: Secreted.
Tissue SpecificityEpithelial tissues and brain.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe ErbB3 gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human HER3
Antigen Species
Human
Gene Name
ERBB3
Gene ID
Protein Name
Receptor tyrosine-protein kinase erbB-3
Uniprot ID
Function
Binds and is activated by neuregulins and NTAK.
Chemical Properties
Molecular WeightTheoretical: 147 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-ERBB3 Polyclonal Antibody | purchase Anti-ERBB3 Polyclonal Antibody | Anti-ERBB3 Polyclonal Antibody cost | order Anti-ERBB3 Polyclonal Antibody | Anti-ERBB3 Polyclonal Antibody molecular weight