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Anti-HIST1H2BJ/Histone H2B.1 Polyclonal Antibody
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Catalog No. TMAB-07054
Anti-HIST1H2BJ/Histone H2B.1 Polyclonal Antibody is a Rabbit antibody targeting HIST1H2BJ/Histone H2B.1. Anti-HIST1H2BJ/Histone H2B.1 Polyclonal Antibody can be used in WB.
Anti-HIST1H2BJ/Histone H2B.1 Polyclonal Antibody
Anti-HIST1H2BJ/Histone H2B.1 Polyclonal Antibody
😃Good
Catalog No. TMAB-07054
Anti-HIST1H2BJ/Histone H2B.1 Polyclonal Antibody is a Rabbit antibody targeting HIST1H2BJ/Histone H2B.1. Anti-HIST1H2BJ/Histone H2B.1 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-HIST1H2BJ/Histone H2B.1 Polyclonal Antibody is a Rabbit antibody targeting HIST1H2BJ/Histone H2B.1. Anti-HIST1H2BJ/Histone H2B.1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Chromosome. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human HIST1H2BJ |
| Antigen Species | Human |
| Gene Name | H2BC11 |
| Gene ID | |
| Protein Name | Histone H2B type 1-J |
| Uniprot ID | |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid. |
| Molecular Weight | Theoretical: 14 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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