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Anti-PXK Polyclonal Antibody

Catalog No. TMAB-11955 Copy Product Info
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Anti-PXK Polyclonal Antibody is a Rabbit antibody targeting PXK. Anti-PXK Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-PXK Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-11955

Anti-PXK Polyclonal Antibody is a Rabbit antibody targeting PXK. Anti-PXK Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-PXK Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PXK Polyclonal Antibody is a Rabbit antibody targeting PXK. Anti-PXK Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human)
Verified Activity
1. Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (PXK) Polyclonal Antibody, Unconjugated (TMAB-11955) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (PXK) Polyclonal Antibody, Unconjugated (TMAB-11955) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Cell membrane. Also associates with the plasma membrane. Isoform 3 is present throughout the cell.
Tissue SpecificityWidely expressed in all tissues examined except in heart. Isoform 1 is expressed in high levels in the brain, skeletal muscle, spleen and testis. Isoform 7 expression has yet to be demonstrated.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PXK
Antigen Species
Human
Gene Name
PXK
Gene ID
Protein Name
PX domain-containing protein kinase-like protein
Uniprot ID
Function
Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity.
Chemical Properties
Molecular WeightTheoretical: 65 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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