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Anti-HMG4/HMGB3 Polyclonal Antibody
Catalog No. TMAB-07179 Copy Product Info
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Anti-HMG4/HMGB3 Polyclonal Antibody is a Rabbit antibody targeting HMG4/HMGB3. Anti-HMG4/HMGB3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-HMG4/HMGB3 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-07179
Anti-HMG4/HMGB3 Polyclonal Antibody is a Rabbit antibody targeting HMG4/HMGB3. Anti-HMG4/HMGB3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-HMG4/HMGB3 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-HMG4/HMGB3 Polyclonal Antibody is a Rabbit antibody targeting HMG4/HMGB3. Anti-HMG4/HMGB3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (mouse bladder); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (HMG4) Polyclonal Antibody, Unconjugated (TMAB-07179) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded (Rat bladder); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (HMG4) Polyclonal Antibody, Unconjugated (TMAB-07179) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Chromosome. |
| Tissue Specificity | Expressed predominantly in placenta. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291]; Nemeth et al., 2006 [PubMed 16945912]).[supplied by OMIM, Mar 2008] |
| Immunogen | KLH conjugated synthetic peptide: human HMG4/HMGB3 |
| Antigen Species | Human |
| Gene Name | HMGB3 |
| Gene ID | |
| Protein Name | High mobility group protein B3 |
| Uniprot ID | |
| Function | Binds preferentially single-stranded DNA and unwinds double stranded DNA. |
| Molecular Weight | Theoretical: 23 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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