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Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2
Catalog No. TMAB-13320 Copy Product Info
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Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2 is a Rabbit antibody targeting Synaptotagmin 1/SYT1. Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2 can be used in WB.
Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2
Copy Product Info🥰Excellent
Catalog No. TMAB-13320
Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2 is a Rabbit antibody targeting Synaptotagmin 1/SYT1. Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2 can be used in WB.
Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2 is a Rabbit antibody targeting Synaptotagmin 1/SYT1. Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Chicken,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | 1. Sample: Cerebrum (Mouse) Lysate at 40 μg Cerebellum (Mouse) Lysate at 40 μg Primary: Anti-Synaptotagmin 1’SYT1 (TMAB-13320) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 48 kD Observed band size: 48 kD 2. Sample: Cerebellum (Mouse) Lysate at 40 μg Primary: Anti-Synaptotagmin 1’SYT1 (TMAB-13320) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 48 kD Observed band size: 48 kD 3. Sample: Cerebral cortex (Mouse) Lysate at 40 μg Cerebrum (Mouse) Lysate at 40 μg Primary: Anti-Synaptotagmin 1’SYT1 (TMAB-13320) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 48 kD Observed band size: 48 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass membrane protein. Cytoplasm. Note=Synaptic vesicles and chromaffin granules. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first C2 domain mediates Ca(2+)-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2. Synaptotagmin may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. |
| Immunogen | KLH conjugated synthetic peptide: human Synaptotagmin 1/SYT1 |
| Antigen Species | Human |
| Gene Name | SYT1 |
| Gene ID | |
| Protein Name | Synaptotagmin-1 |
| Uniprot ID | |
| Function | May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. |
| Molecular Weight | Theoretical: 48 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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