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Anti-DIRC2 Polyclonal Antibody

Catalog No. TMAB-05167 Copy Product Info
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Anti-DIRC2 Polyclonal Antibody is a Rabbit antibody targeting DIRC2. Anti-DIRC2 Polyclonal Antibody can be used in WB.

Anti-DIRC2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-05167

Anti-DIRC2 Polyclonal Antibody is a Rabbit antibody targeting DIRC2. Anti-DIRC2 Polyclonal Antibody can be used in WB.

Anti-DIRC2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-DIRC2 Polyclonal Antibody is a Rabbit antibody targeting DIRC2. Anti-DIRC2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Pig,Horse,Rabbit,Sheep)
Verified Activity
Sample: HepG2 (Human) Cell Lysate at 40 μg
Primary: Anti-DIRC2 (TMAB-05167) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kD
Observed band size: 52 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationLysosome membrane; Multi-pass membrane protein.
Tissue SpecificityUbiquitous. Expressed in proximal tubular cells of the kidney.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundBelonging to the major facilitator superfamily, DIRC2 (disrupted in renal carcinoma protein 2) is a 478 amino acid multi-pass membrane protein that is primarily expressed in kidney proximal tubular cells. The genes encoding DIRC2 and DIRC3 are located at a translocation breakpoint which occurs frequently in individuals affected by familial renal cell carcinoma. Fusion transcripts that result from these translocations may affect normal protein function. This evidence suggests that, due to its chromosomal location, deregulation of the DIRC2 gene may cause haploinsufficiency and therefore result in the onset of tumor growth. There are two isoforms of DIRC2 which are produced as a result of alternative splicing events.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human DIRC2
Antigen Species
Human
Gene Name
SLC49A4
Gene ID
Protein Name
Solute carrier family 49 member 4
Uniprot ID
Function
Electrogenic metabolite transporter.
Chemical Properties
Molecular WeightTheoretical: 52 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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