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Anti-DIRC2 Polyclonal Antibody
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Catalog No. TMAB-05167 Copy Product Info
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Anti-DIRC2 Polyclonal Antibody is a Rabbit antibody targeting DIRC2. Anti-DIRC2 Polyclonal Antibody can be used in WB.
Anti-DIRC2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $221 | 7-10 days | 7-10 days | |
| 100 µL | $371 | 7-10 days | 7-10 days | |
| 200 µL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-DIRC2 Polyclonal Antibody is a Rabbit antibody targeting DIRC2. Anti-DIRC2 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Pig,Horse,Rabbit,Sheep) |
| Verified Activity | Sample: HepG2 (Human) Cell Lysate at 40 μg Primary: Anti-DIRC2 (TMAB-05167) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 52 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Lysosome membrane; Multi-pass membrane protein. |
| Tissue Specificity | Ubiquitous. Expressed in proximal tubular cells of the kidney. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Belonging to the major facilitator superfamily, DIRC2 (disrupted in renal carcinoma protein 2) is a 478 amino acid multi-pass membrane protein that is primarily expressed in kidney proximal tubular cells. The genes encoding DIRC2 and DIRC3 are located at a translocation breakpoint which occurs frequently in individuals affected by familial renal cell carcinoma. Fusion transcripts that result from these translocations may affect normal protein function. This evidence suggests that, due to its chromosomal location, deregulation of the DIRC2 gene may cause haploinsufficiency and therefore result in the onset of tumor growth. There are two isoforms of DIRC2 which are produced as a result of alternative splicing events. |
| Immunogen | KLH conjugated synthetic peptide: human DIRC2 |
| Antigen Species | Human |
| Gene Name | SLC49A4 |
| Gene ID | |
| Protein Name | Solute carrier family 49 member 4 |
| Uniprot ID | |
| Function | Electrogenic metabolite transporter. |
| Molecular Weight | Theoretical: 52 kDa. Actual: 52 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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