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Anti-DIRC2 Polyclonal Antibody

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Catalog No. TMAB-05167

Anti-DIRC2 Polyclonal Antibody is a Rabbit antibody targeting DIRC2. Anti-DIRC2 Polyclonal Antibody can be used in WB.

Anti-DIRC2 Polyclonal Antibody

Anti-DIRC2 Polyclonal Antibody

😃Good
Catalog No. TMAB-05167
Anti-DIRC2 Polyclonal Antibody is a Rabbit antibody targeting DIRC2. Anti-DIRC2 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-DIRC2 Polyclonal Antibody is a Rabbit antibody targeting DIRC2. Anti-DIRC2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Pig,Horse,Rabbit,Sheep)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationLysosome membrane; Multi-pass membrane protein.
Tissue SpecificityUbiquitous. Expressed in proximal tubular cells of the kidney.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundBelonging to the major facilitator superfamily, DIRC2 (disrupted in renal carcinoma protein 2) is a 478 amino acid multi-pass membrane protein that is primarily expressed in kidney proximal tubular cells. The genes encoding DIRC2 and DIRC3 are located at a translocation breakpoint which occurs frequently in individuals affected by familial renal cell carcinoma. Fusion transcripts that result from these translocations may affect normal protein function. This evidence suggests that, due to its chromosomal location, deregulation of the DIRC2 gene may cause haploinsufficiency and therefore result in the onset of tumor growth. There are two isoforms of DIRC2 which are produced as a result of alternative splicing events.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human DIRC2
Antigen Species
Human
Gene Name
SLC49A4
Gene ID
Protein Name
Solute carrier family 49 member 4
Uniprot ID
Function
Electrogenic metabolite transporter.
Chemical Properties
Molecular WeightTheoretical: 52 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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