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Anti-CYT 19 Polyclonal Antibody

Catalog No. TMAB-04920 Copy Product Info
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Anti-CYT 19 Polyclonal Antibody is a Rabbit antibody targeting CYT 19. Anti-CYT 19 Polyclonal Antibody can be used in WB.

Anti-CYT 19 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-04920

Anti-CYT 19 Polyclonal Antibody is a Rabbit antibody targeting CYT 19. Anti-CYT 19 Polyclonal Antibody can be used in WB.

Anti-CYT 19 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CYT 19 Polyclonal Antibody is a Rabbit antibody targeting CYT 19. Anti-CYT 19 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Chicken,Dog,Cow,Horse,Rabbit,Sheep)
Verified Activity
1. Sample:
heart (Mouse) Lysate at 40 μg
liver (Mouse) Lysate at 40 μg
Primary: Anti-CYT 19 (TMAB-04920) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 48 kD
2. Protein: Heart (Mouse) lysate at 40 μg;
Primary: rabbit Anti-CYT 19 (TMAB-04920) at 1:300;
Secondary: HRP conjugated Goat-Anti-rabbit IgG at 1: 5000;
Predicted band size: 42 kD
Observed band size: 42 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundFormation of methylated metabolites is a critical step in the metabolism of inorganic arsenic. Arsenite methyltransferase (cyt19) is localized to the cytoplasm and operates in the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate which is reduced to methylarsonite. Methylarsonite acts as a substrate and is converted into a much less toxic compound dimethylarsinate. cyt19 is highly expressed in liver. Inherited variation in cyt19 may contribute to variation in arsenic metabolism and possibly arsenic-dependent carcinogenesis in humans.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CYT 19
Antigen Species
Human
Gene Name
AS3MT
Gene ID
Protein Name
Arsenite methyltransferase
Uniprot ID
Function
Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH.
Chemical Properties
Molecular WeightTheoretical: 42 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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