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Anti-CPSF2 Polyclonal Antibody
Catalog No. TMAB-04619 Copy Product Info
🥰Excellent
Anti-CPSF2 Polyclonal Antibody is a Rabbit antibody targeting CPSF2. Anti-CPSF2 Polyclonal Antibody can be used in WB.
Anti-CPSF2 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-04619
Anti-CPSF2 Polyclonal Antibody is a Rabbit antibody targeting CPSF2. Anti-CPSF2 Polyclonal Antibody can be used in WB.
Anti-CPSF2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CPSF2 Polyclonal Antibody is a Rabbit antibody targeting CPSF2. Anti-CPSF2 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Chicken,Cow,Horse,Rabbit) |
| Verified Activity | Sample: Hela (Human) Cell Lysate at 30 μg Siha (Human) Cell Lysate at 30 μg Primary: Anti-CPSF2 (TMAB-04619) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 88 kD Observed band size: 88 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nuclear. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | CPSF contains four subunits and localizes to the nucleoplasm where it recognizes the AAUAAA signal in pre-mRNA and interacts with other proteins to facilitate RNA cleavage and poly(A) synthesis (1,4,5). The human CPSF2 gene maps to chromosome 14q32.12 and encodes the second largest subunit of cleavage and polyadenylation specificity factor. U1 snRNP-A protein (U1A) interacts with and affects the activity of CPSF by stabilizing the interaction of CPSF with the AAUAAA-containing RNAs to increase the efficiency of polyadenylation . |
| Immunogen | KLH conjugated synthetic peptide: human CPSF2 |
| Antigen Species | Human |
| Gene Name | CPSF2 |
| Gene ID | |
| Protein Name | Cleavage and polyadenylation specificity factor subunit 2 |
| Uniprot ID | |
| Function | CPSF2 belongs to the RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily. It is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3 prime-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. A poly(A) tail is added to eukaryotic mRNA precursors after tightly coupled cleavage and polyadenylation reactions at their 3-prime ends. |
| Molecular Weight | Theoretical: 88 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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