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Anti-gamma catenin Polyclonal Antibody

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Catalog No. TMAB-06318

Anti-gamma catenin Polyclonal Antibody is a Rabbit antibody targeting gamma catenin. Anti-gamma catenin Polyclonal Antibody can be used in WB.

Anti-gamma catenin Polyclonal Antibody

Anti-gamma catenin Polyclonal Antibody

😃Good
Catalog No. TMAB-06318
Anti-gamma catenin Polyclonal Antibody is a Rabbit antibody targeting gamma catenin. Anti-gamma catenin Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-gamma catenin Polyclonal Antibody is a Rabbit antibody targeting gamma catenin. Anti-gamma catenin Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell junction, adherens junction. Cell junction, desmosome. Cytoplasm, cytoskeleton. Membrane. Cytoplasmic in a soluble and membrane-associated form.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Cateninma gamma
Antigen Species
Human
Gene Name
JUP
Gene ID
Protein Name
Junction plakoglobin
Uniprot ID
Function
Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.
Chemical Properties
Molecular WeightTheoretical: 82 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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