Anti-PSMA7 Polyclonal Antibody is a Rabbit antibody targeting PSMA7. Anti-PSMA7 Polyclonal Antibody can be used in WB.

IgG

Mouse (predicted:Human,Rat,Pig,Sheep,Cow,Dog,Horse)

25 μg total protein per lane of various lysates (see on figure) probed with PSMA7 polyclonal antibody, unconjugated (TMAB-11863) at 1:500 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.

WB: 1:500-2000

Polyclonal

KLH conjugated synthetic peptide: human PSMA7

Human

PSMA7

Proteasome subunit alpha type-7

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.