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Anti-Phospho-RASGRF1 (Ser929) Polyclonal Antibody

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Catalog No. TMAB-11223

Anti-Phospho-RASGRF1 (Ser929) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RASGRF1 (Ser929). Anti-Phospho-RASGRF1 (Ser929) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Phospho-RASGRF1 (Ser929) Polyclonal Antibody

Anti-Phospho-RASGRF1 (Ser929) Polyclonal Antibody

Copy Product Info
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Catalog No. TMAB-11223
Anti-Phospho-RASGRF1 (Ser929) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RASGRF1 (Ser929). Anti-Phospho-RASGRF1 (Ser929) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Phospho-RASGRF1 (Ser929) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RASGRF1 (Ser929). Anti-Phospho-RASGRF1 (Ser929) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Sheep)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Phospho-RASGRF1 (Ser929)) Polyclonal Antibody, Unconjugated (TMAB-11223) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: human RasGRF1 around the phosphorylation site of Ser929
Antigen Species
Human
Gene Name
RASGRF1
Gene ID
Protein Name
Ras-specific guanine nucleotide-releasing factor 1
Uniprot ID
Function
Promotes the exchange of Ras-bound GDP by GTP.
Chemical Properties
Molecular WeightTheoretical: 145 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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