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Anti-Lamin B Receptor Polyclonal Antibody
😃Good
Catalog No. TMAB-08197
Anti-Lamin B Receptor Polyclonal Antibody is a Rabbit antibody targeting Lamin B Receptor. Anti-Lamin B Receptor Polyclonal Antibody can be used in WB,FCM.
Anti-Lamin B Receptor Polyclonal Antibody
Anti-Lamin B Receptor Polyclonal Antibody
😃Good
Catalog No. TMAB-08197
Anti-Lamin B Receptor Polyclonal Antibody is a Rabbit antibody targeting Lamin B Receptor. Anti-Lamin B Receptor Polyclonal Antibody can be used in WB,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Lamin B Receptor Polyclonal Antibody is a Rabbit antibody targeting Lamin B Receptor. Anti-Lamin B Receptor Polyclonal Antibody can be used in WB,FCM. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus inner membrane; Multi-pass membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death. |
| Immunogen | KLH conjugated synthetic peptide: human Lamin B Receptor |
| Antigen Species | Human |
| Gene Name | LBR |
| Gene ID | |
| Protein Name | delta(14)-sterol reductase LBR |
| Uniprot ID | |
| Function | Anchors the lamina and the heterochromatin to the inner nuclear membrane. |
| Molecular Weight | Theoretical: 68 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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