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Anti-Lamin B Receptor Polyclonal Antibody
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Catalog No. TMAB-08197 Copy Product Info
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Anti-Lamin B Receptor Polyclonal Antibody is a Rabbit antibody targeting Lamin B Receptor. Anti-Lamin B Receptor Polyclonal Antibody can be used in WB,FCM.
Anti-Lamin B Receptor Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Lamin B Receptor Polyclonal Antibody is a Rabbit antibody targeting Lamin B Receptor. Anti-Lamin B Receptor Polyclonal Antibody can be used in WB,FCM. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus inner membrane; Multi-pass membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death. |
| Immunogen | KLH conjugated synthetic peptide: human Lamin B Receptor |
| Antigen Species | Human |
| Gene Name | LBR |
| Gene ID | |
| Protein Name | delta(14)-sterol reductase LBR |
| Uniprot ID | |
| Function | Anchors the lamina and the heterochromatin to the inner nuclear membrane. |
| Molecular Weight | Theoretical: 68 kDa. Actual: 68 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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