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Anti-SIGLEC11 Polyclonal Antibody
😃Good
Catalog No. TMAB-12792
Anti-SIGLEC11 Polyclonal Antibody is a Rabbit antibody targeting SIGLEC11. Anti-SIGLEC11 Polyclonal Antibody can be used in WB.
Anti-SIGLEC11 Polyclonal Antibody
Anti-SIGLEC11 Polyclonal Antibody
😃Good
Catalog No. TMAB-12792
Anti-SIGLEC11 Polyclonal Antibody is a Rabbit antibody targeting SIGLEC11. Anti-SIGLEC11 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-SIGLEC11 Polyclonal Antibody is a Rabbit antibody targeting SIGLEC11. Anti-SIGLEC11 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed by macrophages in various tissues including Kupffer cells. Also found in brain microglia. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. This family member mediates anti-inflammatory and immunosuppressive signaling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| Immunogen | KLH conjugated synthetic peptide: human SIGLEC11 |
| Antigen Species | Human |
| Gene Name | SIGLEC11 |
| Gene ID | |
| Protein Name | Sialic acid-binding Ig-like lectin 11 |
| Uniprot ID | |
| Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. |
| Molecular Weight | Theoretical: 74 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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