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Cat No. | Product Name | Synonyms | Targets |
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TP1304 | Compstatin | Complement System | |
Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor. | |||
T7477 | Antazoline | Others | |
Antazoline has antihistamine and anticholinergic effects.It used to treat a variety of arrhythmias. | |||
T12851 | SB290157 trifluoroacetate | Complement System | |
SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM). | |||
T9357 | Ro 5212773 | Epptb | Others |
Ro 5212773 (Epptb) is a selective TAAR1 antagonist. | |||
T9915 | Eculizumab | Complement System | |
Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5 | |||
T8509 | Danicopan | ACH-4471 | Complement System |
Danicopan (ACH-4471) (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits the activity of the ... | |||
T9189 | Iptacopan hydrochloride | Iptacopan HCl,LNP023 hydrochloride | Complement System |
Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. Iptacopan hydrochloride shows direct, reversible, and high-affinity b... | |||
T38332 | Complement factor D-IN-2 | Complement System | |
Complement factor D-IN-2 is an inhibitor of Complement factor D and reduces the excessive activation of complement factor D. | |||
T6579 | Medetomidine hydrochloride | MPV785,Medetomidine HCl,Domitor | Adrenergic Receptor |
Medetomidine hydrochloride (MPV785) is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor. | |||
T3638 | Leukadherin-1 | Integrin , Complement System | |
Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendothelial migration; reduces inflammation. | |||
T16849 | SB-222200 | Neurokinin receptor | |
SB-222200 is a selective, reversible, and competitive antagonist of the human NK-3 receptor(Ki=4.4 nM). | |||
TQ0091 | LY2795050 | Opioid Receptor | |
LY2795050 is a novel specific κ-Opioid Receptor antagonist (IC50: 0.72 nM). | |||
T17250 | W-54011 | ROS , Complement System | |
W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki: 2.2 nM). W-54011 inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and g... | |||
T7748 | Dermorphin TFA | Others , Opioid Receptor | |
Dermorphin TFA is a new class of opioids-like peptides | |||
T28352 | PDE9-IN-(S)-C33 | (S)-C33 | PDE |
PDE9-IN-(S)-C33 ((S)-C33) is a potent and selective inhibitor of PDE9 (IC50 = 11 nM). PDE9-IN-(S)-C33 can be used for central nervous system diseases and diabetes research. | |||
T8745 | PROTAC BRAF-V600E degrader-1 | Compound 23 | Raf |
PROTAC BRAF-V600E degrader-1 (Compound 23) selectively induces degradation of BRAF-V600E but not wildtype BRAF. | |||
T7776 | ADH-503 | GB1275 | Complement System |
ADH-503 (GB1275) is a potent agonist of the integrin CD11b to mitigate myeloid cell immunosuppression. | |||
T4405 | Ceftibuten dihydrate | Sch-39720 dihydrate | Antibacterial , Antibiotic |
Ceftibuten dihydrate (Sch-39720 dihydrate) is the dihydrate form of ceftibuten, and is a third-generation cephalosporin with antibacterial activity. | |||
T2227 | Hemicholinium 3 | Hemicholinium-3,Hemicholine | Others , AChE |
Hemicholinium 3 is a potent and selective choline uptake blocker. | |||
T13554 | Arimoclomol maleate | BRX-220 | HSP |
Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer. | |||
T9316 | JR14a | 5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride | Complement System |
JR14a (5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride) is a potent antagonist of human complement C3a receptor. | |||
T19333 | Gadoteridol | ProHance,SQ-32692,Gd-HP-DO3A | Others |
Gadoteridol (Gd-HP-DO3A) is a gadolinium-based MRI contrast agent that can be used for central nervous system imaging. | |||
T23008L | MMPIP hydrochloride | MMPIP hydrochloride (479077-02-6 Free base) | GluR |
MMPIP hydrochloride is a selective antagonist of allosteric mGluR7. MMPIP hydrochloride can be used in research on the roles of mGluR7 on central nervous system functions. | |||
T13553 | Arimoclomol | BRX-220 free base | HSP |
Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS). | |||
T6666 | Sevelamer Carbonate | Others | |
Sevelamer carbonate is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as the counterion. | |||
T0370 | Pheniramine maleate | Daneral,Inhiston,Trimetose | 5-HT Receptor , Histamine Receptor |
Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re... | |||
T1076 | Dexamethasone | MK 125,Prednisolone F,NSC 34521,Hexadecadrol | Glucocorticoid Receptor , Mitophagy , IL Receptor , SARS-CoV , Antibacterial , Antibiotic , Autophagy , Complement System |
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and an IL receptor modulator. Dexamethasone has anti-inflammatory and immunosuppressive activity and induces autophagy. Dexamethasone inhibits LPS-induced... | |||
TP1793 | Nociceptin (1-13), amide | Opioid Receptor | |
Nociceptin (1-13), amide is a potent ORL1 (OP4) receptor agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes. | |||
T23044 | N,N'-Dicyclohexylurea | DCU,1,3-Dicyclohexylurea,NSC 17013,Dicyclohexylurea,Dicyclohexylcarbodiamide,AURORA KA-3582 | Epoxide Hydrolase |
N,N'-Dicyclohexylurea (AURORA KA-3582) is a soluble epoxide hydrolase (sEH) inhibitor. | |||
T7404 | Dermorphin | Opioid Receptor | |
Dermorphin is agonist of μ-opioid receptor (MOR) agonist. | |||
T7497 | C3a (70-77) | Complement 3a (70-77),C3a 70-77 | Complement System |
C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a. | |||
T13379 | (Z)-Leukadherin-1 | ADH-503 free base | Complement System |
(Z)-Leukadherin-1 (ADH-503 free base) is an allosteric agonist of CD11b. | |||
TP1843L | Systemin acetate(137181-56-7 free base) | Others | |
Systemin acetate is an 18-amino acid polypeptide with the sequence AVQSKPPSKRDPPKMQTD that is found in Solanaceae plants (such as tomato and potato). | |||
TP1843 | Systemin | ||
Systemin is an 18-amino acid polypeptide with the sequence AVQSKPPSKRDPPKMQTD that is found in Solanaceae plants (such as tomato and potato). | |||
T35009 | Vadocaine | Vadocaina,Vadocainum | Others |
Vadocaine (Vadocaina) is a novel analgesic compound for local anaesthesia and can be used to study the central nervous system and cardiovascular system. | |||
T13260 | Gastrin/CCK antagonist 1 | cholecystokinin | |
Gastrin/CCK antagonist 1 is a potent gastrin/CCK antagonist for the study of metabolic system-related diseases. | |||
T27303 | Farglitazar | GI-262570,GI 262570,GI262570 | |
Farglitazar is a PPAR-γ agonist. GI262570 stimulates the ENaC and Na,K-ATPase system resulting in the increasing of water and sodium reabsorption in distal nephron. | |||
TNU0123 | 5-Methoxyuridine | Mo5U | Apoptosis |
5-Methoxyuridine (Mo5U) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.5-Methoxyuridine's anticancer mechanism i... | |||
T9442 | 4-Chloro-3-nitrobenzoic acid | Others | |
4-Chloro-3-nitrobenzoic acid is a nitric oxide scavenger and has been used to study the effects of nitric oxide on the cardiovascular system and the effects of nitric oxide on the immune system. | |||
T13423L | (1S,2R)-2-PCCA | (1S,2R)-2-PCCA(Iso-1609563-71-4) | GPR |
(1S,2R)-2-PCCA is a novel and potent small molecule GPR88 receptor agonist with an EC50 value of 3 nM in the non-cellular system and 603 nM in the cellular system. | |||
T68079 | Gedocarnil | ZK 113315,SH 530 | Others |
Gedocarnil(ZK 113315) may be used to study diseases of the central nervous system. | |||
T1118L | Cefprozil | Cefprozilum,Cefprozilo,Cefzil,Brisoral,Cefprozil anhydrous | Antibacterial , Antibiotic |
Cefprozil (Cefzil) is a novel cephalosporin antibiotic with antiviral activity for the study of immune system disorders. | |||
T10503 | ACAT-IN-1 cis isomer | Acyltransferase | |
ACAT-IN-1 cis isomer is a potent ACAT inhibitor (IC50: 100 nM) for the study of immune system-related diseases. | |||
T63272 | Edralbrutinib | TG-1701 | BTK |
Edralbrutinib (TG-1701) is a potent BTK inhibitor with anticancer activity and is used in the treatment of tumors, immune system disorders, and blood and lymphatic system disorders.Edralbrutinib is used in the study of m... | |||
T27795 | Landipirdine | RO 5025181,RO5025181,SYN-120,SYN120,RO-5025181,SYN 120 | 5-HT Receptor |
Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia. | |||
T16792 | Rovazolac | ALX-101 | Liver X Receptor |
Rovazolac (ALX-101) is a liver x receptor (LXR) modulator used in the study of immune system disorders and atopic dermatitis. | |||
T7065 | Tizanidine | Adrenergic Receptor | |
Tizanidine, an α2-adrenergic receptor agonist, suppresses the release of neurotransmitters from central nervous system (CNS) noradrenergic neurons. | |||
T8438 | 4i | CHEMBL1269981,5-HT3 antagonist-4i | 5-HT Receptor |
4i (CHEMBL1269981) is a 5-HT3 receptor antagonist,It modulates the serotonergic system. | |||
T1597 | Proadifen hydrochloride | U-5446,RP-5171,SKF-525A | P450 |
Proadifen hydrochloride (RP-5171) is an inhibitor of drug metabolism and cytochrome P-450 enzyme system activity. | |||
T77676 | (Z)-Metanicotine 2HCl | (Z)-Metanicotine 2HCl(1129-68-6 Free base) | Others |
(Z)-Metanicotine 2HCl has analgesic activity and is used in the treatment of central system disorders. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19189 | Allocholic acid | Others | |
Allocholic acid is a fetal bile acid found in vertebrates and reappears during liver regeneration and carcinogenesis. It is also a potent and specific stimulant of the adult olfactory system. | |||
T2S1720 | Huperzine B | AChE | |
1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's disease therapy. | |||
T21164 | Sulfentrazone | FP-846 | Others |
Sulfentrazone (FP-846) is purified form of sulfentrazone which acts as a protoporphyrinogen oxidase inhibitor.It is a phenyl triazolinone herbicide | |||
T0945 | Cyclosporin A | Cyclosporine A,Ciclosporin,Cyclosporine | Phosphatase , Antibiotic , Complement System |
Cyclosporin A is a naturally occurring cyclic polypeptide that is the active metabolite of a fungus. Cyclosporin A is an immunosuppressant that binds to procyclins and inhibits calcineurin (IC50=7 nM). | |||
T2S1464 | Thiocolchicoside | Thiocolchicine 2-glucoside analog,Coltramyl | Others , GABA Receptor |
Thiocolchicoside (Thiocolchicine 2-glucoside analog) (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine rece... | |||
T0508 | γ-Aminobutyric acid | Gamma-aminobutyric acid,4-Aminobutyric acid,GABA,4-Aminobutanoic acid,Piperidic acid | GABA Receptor , Endogenous Metabolite |
γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system. | |||
T4853 | TRIA-662 | 3-Carbamoyl-1-methylpyridinium Chloride,1-Methylnicotinamide chloride,1-methylpyridin-1-ium-3-carboxamide hydrochloride,Nicotinamide Chloromethylate | Others , Endogenous Metabolite |
TRIA-662 (Nicotinamide Chloromethylate) is a niacin metabolite excreted via the urinary system. | |||
T3920 | Pseudoginsenoside F11 | Ginsenoside A1 | Others , Endogenous Metabolite |
Pseudoginsenoside F11 (Ginsenoside A1) is a component of Panax quinquefolium (American ginseng) which main pharmacological activities are positive inotropic effect on isolated heart function, good therapeutic effect on m... | |||
TL0001 | Dencichine | L-Dencichin,ODAP,Dencichin | Others , HIF/HIF Prolyl-Hydroxylase |
Dencichine (ODAP) is a neurotoxic agent. Dencichine is a haemostatic agent, the hemostatic effect relates to modulation of the coagulation system, platelet aggregation and fibrinolytic system. It has renoprotective effec... | |||
T1396 | Bemegride | Bemegrid,3-Ethyl-3-methylglutarimide,Agipnon | GABA Receptor |
Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning. | |||
T22300 | Creatine monohydrate | Methylguanidoacetic acid monohydrate | Others , Endogenous Metabolite |
Creatine monohydrate (Methylguanidoacetic acid monohydrate) is a key player in the phosphagen energy system, especially in muscle and the brain. Creatine monohydrate is the primary source of ATP during high-intensity, sh... | |||
T13802 | Oleamide | Oleic acid amide | Others , Endogenous Metabolite |
Oleamide (Oleic acid amide) is an endogenous fatty acid amide and can be used in the synthesis of de novo in the mammalian nervous system. | |||
T2911 | Stevioside | TLR | |
A natural, noncaloric sweetener with a potency 300 times more than that of regular sucrose. Exhibits transepithelial p-aminohippurate transport via organic anion transport system interference. | |||
T4797 | DEHP | Bis(2-ethylhexyl) phthalate | Others , Endogenous Metabolite |
DEHP (Bis(2-ethylhexyl) phthalate) is used to impart softness and flexibility to PVC products. DEHP has been implicated in obesity and insulin resistance. DEHP inhibits prostaglandin synthesis and adversely affects the e... | |||
T19538 | (R)-(-)-1,3-Butanediol | Endogenous Metabolite | |
(R)-(-)-1,3-Butanediol is a novel ketogenic ester that rapidly increases circulating concentrations of r- and s-ß-hydroxybutyric acid in healthy adults in a short period of time and can be used to study metabolic system-... | |||
T6751 | Acetylcholine iodide | Acetylcolina | Others |
Acetylcholine iodide (Acetylcolina) is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the cent... | |||
T6S0627 | Mesaconitine | TNF | |
1. Mesaconitine has antiinflammatory activity. 2. Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system. | |||
T4S0790 | Diosbulbin B | Others | |
1. Diosbulbin B exhibits potential hepatotoxicity. 2. Diosbulbin B has potential anti-tumor effects which may be related to influencing the immune system for the first time. | |||
T8790 | 1-Methylhistamine dihydrochloride | Endogenous Metabolite | |
1-Methylhistamine dihydrochloride is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism. It has been used as a biomarker of histaminergic system activity in the brains... | |||
T40646 | Lipoteichoic acid | Complement System | |
Lipoteichoic acid, a polymer of Staphylococcus aureus cell wall, activates the complement system by inducing C3 and inhibiting CD55, and reduces fat deposition via the IGF-1 pathway. | |||
T6758 | Anisomycin | Flagecidin,NSC 76712,Wuningmeisu C | Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic , JNK |
Anisomycin (NSC-76712) is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system. | |||
TN6982 | Diethyl phthalate | 1,2-diethyl benzene-1,2-dicarboxylate | Apoptosis |
Diethyl phthalate (1,2-diethyl benzene-1,2-dicarboxylate) is a endocrine disrupter affecting the apoptotic system in PC12 cells. Diethyl phthalate is widely used in many plastics and personal care products. | |||
TN3695 | Coniine hydrochloride | Others | |
Coniine hydrochloride, a polyketide-derived alkaloid, is poisonous to humans and animals. It is a nicotinic acetylcholine receptor antagonist, which leads to inhibition of the nervous system. | |||
T3383 | Cimifugin | Cimitin | Others |
Cimifugin (Cimitin) inhibits NO production induced by lipopolysaccharide in macrophage cell line RAW 264.7 and for 1, 1-diphenyl-2-picrylhydrazyl free-radical scavenging activity in cell-free bioassay system. | |||
T3S1250 | Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside | Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside | Others |
Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside) is a natural product, and has good pharmacological effects on the cardiovascular system. | |||
T9510 | 1,2-Distearoyl-sn-glycero-3-phosphorylcholine | DSPC,L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL,1,2-Distearoyl-sn-glycero-3-PC | Others |
1,2-Distearoyl-sn-glycero-3-phosphorylcholine (L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL) is a cylindrical-shaped lipid used to synthesize liposomes. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (L-ALPHA-PHOSPHATIDYLCHOLI... | |||
T14046 | Anandamide | (5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide | Cannabinoid Receptor , Endogenous Metabolite |
Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) in the central nervous sy... | |||
T8072 | S-Methyl-L-cysteine | S-Methylcysteine | Antioxidant , Reactive Oxygen Species |
S-Methyl-L-cysteine (S-Methylcysteine) is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with neuroprotective, antioxidative, and anti-... | |||
T4S1990 | Carvacrol | Karvakrol,O-Thymol,cymophenol | Apoptosis , Others , Gamma-secretase , Endogenous Metabolite , Antifungal |
1. Carvacrol (O-Thymol) presents anxiolytic effects. 2. 5-Isopropyl-2-methylphenol presents antinociceptive activity. 3. Carvacrol presents antidepressant effects, seems to be dependent on its interaction with the dopami... | |||
T2596 | N-Acetyl-β-Asp-Glu | Others | |
N-Acetyl-β-Asp-Glu is a peptide neurotransmitter, the third most common neurotransmitter in the mammalian nervous system. NAAG consists of N-acetylaspartate (NAA) and glutamate coupled via a peptide bond. | |||
T2838 | Naringenin | Naringetol,S-Dihydrogenistein,Pelargidanon,Salipurol,NSC 11855,NSC 34875 | P450 , Influenza Virus , Reactive Oxygen Species , Endogenous Metabolite , PPAR |
Naringenin (NSC-11855) is a flavanone that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, antiinflammatory, carbohydrate metabolism promoter, immunity system modulater. T... | |||
TN2233 | Spathulenol | Antioxidant , Antifungal | |
Spathulenol is a natural ingredient from Aristolochia yunnanensis that has anti-inflammatory, antioxidant, anti-proliferation, anti-ulcer and anti-mycobacterium activities. Spathulenol showed significant antioxidant acti... | |||
T6630 | Quercetin Dihydrate | Sophoretin | Apoptosis , PI3K |
Quercetin Dihydrate (Sophoretin) is a polyphenolic flavonoid that was found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine. It is used for their nervous system and anticancer effect... | |||
T0465 | Ellagic acid | Gallogen,Elagostasine | Hedgehog/Smoothened , Casein Kinase , Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , PKA , Syk , PKC , Carbonic Anhydrase |
Ellagic acid (Gallogen) is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clotting system which also causes kinin release; used... | |||
T1429 | 17α-Hydroxyprogesterone | Hydroxyprogesterone,17-OHP,17-Hydroxyprogesterone | Estrogen/progestogen Receptor , Progesterone Receptor , Endogenous Metabolite |
17α-Hydroxyprogesterone (17-OHP) is a physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester of pregnancy. Hydroxyprogesterone binds to th... | |||
T4779 | 4-Methylcatechol | p-Methylcatechol,Homocatechol,4-methylbenzene-1,2-diol,3,4-Dihydroxytoluene | Others , Endogenous Metabolite |
4-Methylcatechol (3,4-Dihydroxytoluene) is a metabolite of homoprotocatechuic acid. It is both a substrate and a suicide inhibitor of Catechol 2,3-dioxygenase. 4-Methylcatechol (3,4-Dihydroxytoluene) is known to induce t... | |||
TN1624 | Ethyl cinnamate | Calcium Channel , ROS , NO Synthase | |
Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction. Ethyl... | |||
T1083 | Theophylline | Theo-24,1,3-Dimethylxanthine | Endogenous Metabolite , HDAC , PDE , Adenosine Receptor , Autophagy |
Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3... | |||
T5558 | Chelidonic acid | Jervaic acid,Jerva acid,γ-Pyrone-2,6-dicarboxylic acid | NF-κB , Caspase |
Chelidonic acid (Jervaic acid) is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid (Jervaic acid) also shows anti-inflammatory activity... | |||
T16340 | Nosiheptide | RP 9671,Multhiomycin | Antibacterial , Antibiotic |
Nosiheptide (Multhiomycin), a thiopeptide antibiotic synthesized by Streptomyces actuosus, serves as a potent feed additive to promote animal growth. It functions by hindering bacterial protein synthesis and is distingui... | |||
TN2322 | Yangambin | Calcium Channel , PAFR | |
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibiti... | |||
T0522 | Diammonium Glycyrrhizinate | Glycyrrhizin | Dehydrogenase |
Diammonium Glycyrrhizinate (Glycyrrhizin) , an extensively used anti-inflammatory agent, is isolated from the licorice root. It is metabolized to glycyrrhetinic acid, which inhibits 11-β-hydroxysteroid dehydrogenase and ... | |||
T3386 | Kaempferitrin | Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside | cell cycle arrest , Glucokinase , IGF-1R |
Kaempferitrin (Lespenephryl) has antidepressant-like effect related to the serotonergic system, principally 5-HT1A. Kaempferitrin exerts cytotoxic and antitumor effects against HeLa cells. Kaempferitrin stimulates glucos... | |||
T2O2777 | L-Threonine | threonine | Others , Endogenous Metabolite |
L-Threonine (threonine) is an essential amino acid in humans,an important amino acid for the nervous system,L-Threonine also plays an important role in porphyrin and fat metabolism and prevents fat buildup in the liver. ... | |||
T4A2458 | Resibufogenin | Bufogenin,Recibufogenin | Others |
1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological eff... | |||
T7931 | 16a,17a-Epoxy-4-Pregnen-3,20-Dione | Others | |
16a,17a-Epoxy-4-Pregnen-3,20-Dione is a synthetic progestin, a metabolite of the luteinizing hormone hormone, which acts by binding to the luteinizing hormone receptor. It has been used to study the effects of progestero... | |||
T3767 | Polygalacic acid | Virgaureagenin G | MMP , AChR , AChE |
Polygalacic acid (Virgaureagenin G)(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acetyltransferase (ChAT) activity, and eleva... | |||
TN1516 | Cnidicin | NOS , NO Synthase | |
Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the pr... | |||
T15248 | Estetrol | Donesta | Estrogen Receptor/ERR , Endogenous Metabolite |
Estetrol(Donesta) is an orally available, selective modulator of the estrogen receptor, a naturally occurring estrogen synthesized by the human fetal liver during pregnancy.Estetrol has effects on the endometrium or cent... | |||
T6S2227 | Spinosin | Flavoayamenin | Others |
1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammato... | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00319 | Type III secretion system needle Protein, Burkholderia thailandensis, Recombinant (His) | Burkholderia thailandensis | Yeast |
TMPY-03503 | GCSH Protein, Human, Recombinant (His) | Human | E. coli |
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoi... | |||
TMPY-02374 | LSAMP Protein, Human, Recombinant (hFc) | Human | HEK293 |
The limbic system-associated membrane protein (LAMP) is a cell surface glycoprotein expressed by cortical and subcortical regions of the mammalian CNS that comprise or receive direct projections from limbic system struct... | |||
TMPY-02383 | LSAMP Protein, Human, Recombinant (His) | Human | HEK293 |
The limbic system-associated membrane protein (LAMP) is a cell surface glycoprotein expressed by cortical and subcortical regions of the mammalian CNS that comprise or receive direct projections from limbic system struct... | |||
TMPJ-01296 | SULT4A1 Protein, Human, Recombinant | Human | E. coli |
Sulfotransferase 4A1 (ST4A1) is a member of the Sulfotransferase 1 family. ST4A1 is highly expressed in the cerebral cortex and frontal lobe, but no expression is detected in the pancreas. ST4A1 is a brain-specific sulfo... | |||
TMPY-03120 | Prostaglandin D2 Synthase Protein, Human, Recombinant (His) | Human | HEK293 |
PTGDS, also known as L-PGDS, belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic mole... | |||
TMPY-02157 | GST Protein, Schistosoma japonicum, Recombinant | Schistosoma japonicum | Baculovirus-Insect Cells |
Genetic engineers have used glutathione S-transferase to create the GST gene fusion system. This system is used to purify and detect proteins of interest. In a GST gene fusion system, the GST sequence is incorporated int... | |||
TMPY-01235 | CD5 Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-02698 | CD14 Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-04870 | Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS1 protein (His) | ZIKV | HEK293 |
Zika virus NS1 antigen is one of seven non-structural proteins. NS1 is involved in RNA replication. The possible effects of NS1 on hosts include: localizes to host cell surface and secreted extracellularly, modulates sig... | |||
TMPY-01741 | CD19 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-05530 | CD19 Protein, Cynomolgus/Rhesus, Recombinant (His), Biotinylated | Cynomolgus,Rhesus | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-05540 | CD19 Protein, Mouse, Recombinant (His), Biotinylated | Mouse | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-03425 | Tau Protein, Human, Recombinant (His) | Human | E. coli |
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are... | |||
TMPY-01282 | CD36 Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-05127 | CD19 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-01949 | CD19 Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-01247 | FLT3 Protein, Human, Recombinant (T227M, His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th... | |||
TMPY-01445 | CD36 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-05427 | CD19 Protein, Human, Recombinant (hFc) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-01302 | CD200R Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-01195 | CD7 Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th... | |||
TMPY-00699 | CD155/PVR Protein, Human, Recombinant (hFc) | Human | HEK293 |
CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall... | |||
TMPY-01386 | CD155/PVR Protein, Human, Recombinant (His) | Human | HEK293 |
CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall... | |||
TMPY-01612 | CD155/PVR Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 |
CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall... | |||
TMPY-01829 | CD83 Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-05277 | IL-4R Protein, Human, Recombinant (hFc) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-01055 | IL-4R Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-01355 | Transglutaminase 2/TGM2 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth an... | |||
TMPY-01459 | TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th... | |||
TMPY-02535 | TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th... | |||
TMPK-00811 | L1CAM Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many huma... | |||
TMPY-03577 | Pleiotrophin/PTN Protein, Mouse, Recombinant | Mouse | Baculovirus-Insect Cells |
HB-GAM belongs to the pleiotrophin family. During embryonic and early postnatal development, HB-GAM is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, ... | |||
TMPY-01199 | CD74 Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-01152 | CD226 Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th... | |||
TMPY-01023 | CD38 Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-02099 | CD63 Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th... | |||
TMPY-01151 | IFNGR1 Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-02813 | ErbB4 Protein, Human, Rhesus, Recombinant (His) | Human,Rhesus | HEK293 |
ERBB4 is a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. ERBB4 is ... | |||
TMPY-01825 | RP105/CD180 Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-04167 | CD63 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th... | |||
TMPY-05573 | CD38 Protein, Human, Recombinant (His), PE conjugated | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-02141 | UPAR/PLAUR Protein, Human, Recombinant (His) | Human | HEK293 |
Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and ... | |||
TMPY-03923 | CD38 Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPJ-01463 | IL-2 Protein, Human, Recombinant (E. coli) | Human | E. coli |
Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system,belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or m... | |||
TMPY-02053 | MICA Protein, Human, Recombinant (His), MICA*018 | Human | HEK293 |
MHC class I chain-related molecules A (MICA) is one of the genes in the HLA class I region, which belongs to the MHC class I family. It is the member of the non-classical class I family that displays the greatest degree ... | |||
TMPY-02355 | IFNGR1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-01257 | UPAR/PLAUR Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and ... | |||
TMPY-05476 | MICA Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
MHC class I chain-related molecules A (MICA) is one of the genes in the HLA class I region, which belongs to the MHC class I family. It is the member of the non-classical class I family that displays the greatest degree ... | |||
TMPY-02424 | Prolactin Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Prolactin (PRL) is a hormone with multiple actions in the central nervous system (CNS) spanning from physiology to pathology. PRL exerts different actions through its receptors that can be found in both neurons and glial... | |||
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Cat No. | Product Name | ||
---|---|---|---|
L4660 | Anti-Nervous System Disease Library | 1246 compounds | |
Well-chosen 1246 compounds with unique structures targeting nervous system; | |||
L2630 | Neuronal Differentiation Compound Library | 680 compounds | |
680 compounds related to neuronal differentiation, suitable for the drug development of nervous system disease. | |||
L2400 | Endocrinology-Hormone Compound Library | 813 compounds | |
A unique collection of 813 compounds targeting endocrine system for high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L7700 | Neural Regeneration Compound Library | 529 compounds | |
A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening; | |||
L8600 | Ubiquitination Compound Library | 214 compounds | |
A unique collection of 214 ubiquitination related small chemicals can be used for high throughput and high content screening; | |||
L7500 | Coagulation and Anticoagulation Compound Library | 154 compounds | |
A unique collection of 154 procoagulation and anticoagulation related compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L2170 | Immuno-Oncology Compound Library | 454 compounds | |
A unique collection of 454 compounds acting on immune-oncology therapeutic targets can be used for high throughput and high content screening; | |||
L2600 | Neuronal Signaling Compound Library | 2540 compounds | |
A unique collection of 2540 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L3300 | Histamine & Melatonin Receptor-Targeted Compound Library | 155 compounds | |
A unique collection of 155 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L4300 | Wnt/Hedgehog/Notch Compound Library | 240 compounds | |
A unique collection of 240 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening; | |||
L3900 | DNA Damage & Repair Compound Library | 937 compounds | |
A unique collection of 937 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L2195 | Anti-Prostate Cancer Compound Library | 2096 compounds | |
2096 compounds associated with prostate cancer that can be used for high-throughput and high-content screening. | |||
L3980 | DNA Damage and Repair Compound Library Plus | 667 compounds | |
Well-chosen 667 compounds with unique structures targeting DNA damage & repair; | |||
L2620 | Anti-Neurodegenerative Disease Compound Library | 2150 compounds | |
A unique collection of 2150 compounds related to neurodegenerative diseases can be used for HTS or HCS; | |||
L6730 | Anti-virus Traditional Chinese Medicine Monomer Library | 270 compounds | |
A collection of 270 TCM monomers with anti-virus activity. An effective tool for drug development and pharmacological studies. | |||
L8700 | Ferroptosis Compound Library | 800 compounds | |
A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study; | |||
L5900 | CNS-Penetrant Compound Library | 516 compounds | |
A unique collection of 516 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L3700 | JAK-STAT Compound Library | 256 compounds | |
A unique collection of 256 JAK/STAT signaling targeted compounds for high throughput and high content screening; | |||
L2800 | Serotonin Receptor-Targeted Compound Library | 275 compounds | |
A unique collection of 275 compounds targeting serotonin receptors for high throughput screening and high content screening; | |||
L6600 | Anti-Gastroenteritis Natural Product Library | 223 compounds | |
A unique collection of 223 natural products related to gastroenteritis for high throughput screening (HTS) and high content screening (HCS); | |||
L6140 | Saccharide and Glycoside Natural Product Library | 364 compounds | |
A unique collection of 364 saccharides and glycosides compounds can be used for HTS and HCS; | |||
L9700 | Endoplasmic Reticulum Stress Compound Library | 193 compounds | |
A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS); | |||
L4700 | Immunology/Inflammation Compound Library | 3483 compounds | |
A unique collection of 3483 anti-inflammation compounds effective for high throughput screening and high content screening. | |||
L2610 | Neurotransmitter Receptor Compound Library | 1513 compounds | |
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening; | |||
L9420 | Exosome Compound Library | 80 compounds | |
80 exosome-related compounds that can be used for high-throughput and high-content screening. | |||
L6210 | Tibetan medicine Compound Library | 754 compounds | |
A collection of 754 natural product molecules originated from Tibetan medicine, which can be used for high-throughput and high-content screening. | |||
L6400 | Marine Natural Product Library | 148 compounds | |
A unique collection of 148 marine natural products for high throughput screening (HTS) and high content screening (HCS); | |||
L9840 | Anti-Alzheimer's Disease Compound Library | 1040 compounds | |
A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS. | |||
L6740 | Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library | 386 compounds | |
A collection of 386 TCM monomers with anti-colorectal activity. An effective tool for drug development and pharmacological studies. | |||
L8500 | HIF-1 Signaling Pathway Compound Library | 1352 compounds | |
A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies; |